Narayanan Krishnamurthi

Courtesy Affiliate, Adjunct Faculty

Adjunct Faculty, School of Life Sciences Interdisciplinary Graduate faculty

College of Nursing & Health Innovation (CONHI) 500 North 3rd Street, O: NHI-I, 378 Arizona State University Phoenix, AZ 85004
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Long Bio

Narayanan Krishnamurthi is an assistant professor in the Edson College of Nursing and Health Innovation at Arizona State University. He received his doctorate from Indian Institute of Technology, Madras, India in the field of biomedical data analyses. Later, he did his postdoctoral fellowship in a unique program, Integrated Rehabilitation Engineering Program (IREP), at Harvard Medical School and Boston University, MA. He joined the College of Nursing and Health Innovation as an assistant professor in 2013.

Krishnamurthi's main research interests include developing therapeutic interventions to preserve function (mobility and quality of life) in aging population, improve/restore function with neurological disorders such as Parkinson's disease. He is also interested in utilizing wearable sensors towards continuous evaluation of gait. His interventions are mainly aimed towards taking advantage of neural plasticity in paradigms that can be effectively utilized in the clinic and/or home environment to facilitate functional recovery. Also, he is interested in quantitative characterization of gait and posture control impairments and cardiovascular and cardiorespiratory dysfunctions.

Education

Ph.D. Biomedical signal analysis, Indian Institute of Technology, Madras, India 1999
M. Sc. Chemistry, Rama Krishna Mission Vivekananda College, Chennai, India 1992
B. Sc. Chemistry, Rama Krishna Mission Vivekananda College, Chennai, India 1990

Research Website URL

Research Website

Research Interests

Dr. Krishnamurthi’s main research interests include developing therapeutic interventions to preserve function (mobility and quality of life) in aging population and improve/restore function with neurological disorders such as Parkinson’s disease and spinal cord injury. His interventions are mainly aimed towards taking advantage of neural plasticity in paradigms that can be effectively utilized in the clinic and/or home environment to facilitate functional recovery. He is also interested in quantitative characterization of gait and posture control impairments and cardiovascular and cardiorespiratory dysfunctions.

Dr. Krishnamurthi has received research grants from National Institutes of Health, Paralyzed Veterans of America Research Foundation, and Arizona State University-Mayo Clinic Seed Grant Program to support his investigations on the effects of polestriding and novel dance training to improve quality of life in Parkinson’s disease and electrical stimulation of legs muscles to alleviate orthostatic hypotension in spinal cord injury. He is also currently investigating the effects of certain deep brain stimulation parameters and a novel real-time feedback paradigm to improve balance and gait in Parkinson’s disease.

Publications

Peer-Reviewed Publications (My first name “Narayanan” is used in some of my earlier publications). (* indicates that Dr. Krishnamurthi is PI of the study; ‡ indicates students co-mentored)

*Krishnamurthi, N., Fleury, J., Belyea, M., Shill, H., & Abbas, J.J. (in press). ReadySteady Intervention to Promote Physical Activity in Older Adults with Parkinson’s Disease: Study Design and Methods. Contemporary Clinical Trials Communications.

‡Muthukrishnan, N., Abbas, J.J., Shill, H., *Krishnamurthi, N. (2019). Cueing Paradigms to Improve Gait and Posture in Parkinson's Disease: A Narrative Review. Sensors, 19, 5468. doi:10.3390/s19245468

Krishnamurthi, N., Murphey, C., & Driver-Dunckley, E. (2019). A Comprehensive Movement and Motion Training Program Improves Mobility in Parkinson’s Disease. Aging, Clinical and Experimental Research. doi: 10.1007/s40520-019-01236-0

‡Bartels, B.M., ‡Moreno, A., ‡Quezada, M.J., ‡Sivertson, H., Abbas, J.J., & *Krishnamurthi, N. (2018). Real-Time Feedback Derived from Wearable Sensors to Improve Gait in Parkinson’s Disease. Technology and Innovation, Special Issue on Technologies for Disabilities, 20, 37-46. N. Krishnamurthi is the PI of the study and the corresponding author.

*Krishnamurthi, N., Shill, H., Stovall, J., O’Donnell, D., Mahant, P., Samanta, J., Lieberman, A., & Abbas, J.J. (2017). Polestriding Intervention Improves Gait and Axial Symptoms in Mild to Moderate Parkinson’s Disease. Archives of Physical Medicine and Rehabilitation, 98, 613-621. N. Krishnamurthi is the PI of the study and the corresponding author.

Link to accompanying podcast: https://soundcloud.com/user-439434772/rehabcast-the-rehabilitation-medi…

Lieberman, A., Krishnamurthi, N., Dhall, R., Salins, N., Pan, D., & Deep, A. (2016). Predicting falls in Parkinson disease patients. Archives of Neuroscience, 3(1), e18646.

‡Jellish, J., Abbas, J.J., Ingalls, T., Mahant, P., Samanta, J., Ospina, M.C., & *Krishnamurthi, N. (2015). A System for Real-Time Feedback to Improve Gait and Posture in Parkinson’s Disease. IEEE Journal of Biomedical and Health Informatics - Special issue on Enabling Technologies in Parkinson’s Disease Management, 19 (6), 1809-1819. N. Krishnamurthi is the PI of the study and the corresponding author.

Lieberman, A., Dhall, R., Salins, N., Sadreddin, A., Moguel-Cobos, G., Karis, J., & Krishnamurthi, N. (2014). Finger Displacement in Parkinson’s Disease: Up? Down? Sideways? The International Journal of Neuroscience, 124 (5), 339-43.

Lieberman, A., Dhall, R., Dhanani, S., Salins, N., Sadreddin, A., Moguel-Cobos, G., Pan, D., Santiago, A., Prigitano, G., Krishnamurthi, N., & Troster, A. (2014). Distinguishing the Tremor of Parkinson’s Disease from Essential Tremor: Finger Displacement. The International Journal of Neuroscience, 124 (3), 175-80.

Lieberman, A., & Krishnamurthi, N. Is There Room for Non-Dopaminergic Treatment in PD? CONy Pro/Con debate (2013). Journal of Neural Transmission, 120 (2), 347-348.

Conovoloff, A., Krishnamurthi, N., Mahant, P., Samanta, J. & Abbas, J.J. (2012). The Effects of Deep Brain Stimulation Amplitude on Motor Performance in Parkinson’s Disease. Journal of Parkinsonism and Restless Legs Syndrome, 2, 73-83.

Lieberman, A., Krishnamurthi, N., Dhall, R., Santiago, A., Moguel-Cobos, G., Sadreddin, A., Husain, S., Salins, N., & Pan, D. (2012). A Simple Question About Falls to Distinguish Balance and Gait Difficulties in Parkinson’s Disease. The International Journal of Neuroscience, 122 (12), 710-715.

Krishnamurthi, N., Mulligan, S., Mahant, P., Samanta, J., & Abbas. J.J. (2012). Deep Brain Stimulation Amplitude Alters Posture Shift Velocity in Parkinson’s Disease. Cognitive Neurodynamics, 6, 325-332.

Iasemidis, L.D., Pardalos, P.M., Shiau, D-S., Chaovalitwongse, W., Narayanan, K., Prasad, A., Tsakalis, K., Carney, P., & Sackellares, J.C. (2005). Long-Term Prospective On-Line Real-Time Seizure Prediction. Clinical Neurophysiology, 116, 532-544.

Veeramani, B., Narayanan, K., Prasad, A., Iasemidis, L.D., Spanias, A., & Tsakalis, K. (2004). Measuring the Direction and the Strength of Coupling in Nonlinear Systems - A Modeling Approach in the State Space. IEEE Signal Processing Letters, 11 (7), 617-620.

Iasemidis, L.D., Pardalos, P.M., Shiau, D-S., Chaovalitwongse, W., Narayanan, K., Sabesan, S., Carney, P., & Sackellares, J.C. (2003). Prediction of Human Epileptic Seizures Based on Optimization and Phase Changes of Brain Electrical Activity. J. Optimization Methods and Software, 18 (1), 81-104.

Narayanan, K., Collins, J.J., Hamner, J., Mukai, S., & Lipsitz, L.A. (2001). Predicting Cerebral Blood Flow Response to Orthostatic Stress from Resting Dynamics: Effects of healthy aging. The American Journal of Physiology, 281: R716-R722.

Narayanan, K., Govindan, R.B., & Gopinathan, M.S. (2000). Evidence for Low Dimension Chaos in Electrically Coupled Chemical Oscillator in Batch Condition, Indian Journal of Chemistry A, 39(1-3), 345-355.

Narayanan, K., Govindan, R.B., & Gopinathan, M.S. (1998). Unstable Periodic Orbits in Human Cardiac Rhythms, Phys. Rev E 57, 4594-4603.

Govindan, R.B., Narayanan, K., & Gopinathan, M.S. (1998). On the Evidence of Deterministic Chaos in ECG: Surrogate and Predictability Analysis, Chaos, 8, 495-502.

PEER-REVIEWED CONFERENCE PROCEEDINGS

‡Som. A., Krishnamurthi, N., Venkataraman, V., Ramamurthy, K., & Turaga, P. (2017). Multiscale Evolution of Attractor-shape Descriptors for Assessing Parkinson's Disease Severity. IEEE GlobalSIP Symposium on Signal and Information Processing for Healthcare Engineering, 938-942.

‡Som, A., Krishnamurthi, N., Venkataraman, V., & Turaga, P. (2016). Attractor-Shape Descriptors for Finer Balance Impairment Assessment in Parkinson’s Disease. International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’16), 3096 – 3100.

‡Tadayon, A., Zia, J., Anantuni, L., McDaniel, T., Krishnamurthi, N., & Panchanathan, S. (2015). A Shoe Mounted System for Parkinsonian Gait Detection and Real-Time Feedback, Communications in Computer and Information Science, 528, 528-533.

Narayanan, K., Mulligan, S., Mahant, P., Samanta, J., & Abbas, J.J. (2007). Effects of Deep Brain Stimulation on Dynamic Posture Shifts in Parkinson’s Disease. IEEE International Conference on Complex Medical Engineering, April 9-11, 1-5.

Sabesan, S., Narayanan, K., Prasad, A., Spanias, A., Sackellares, J.C., & Iasemidis, L.D. (2003). Predictability Of Epileptic Seizures: A Comparative Study Using Lyapunov Exponent and Entropy-Based Measures. Biomedical Sciences Instrumentation, 39, 129-35.

Veeramani, B., Prasad, A., Narayanan, K., Spanias, A., L.D. Iasemidis, L.D. (2003). Measuring Information Flow in Nonlinear Systems - A Modeling Approach in the State Space. Biomed Sciences Instrumentation, 39, 65-70.

Venugopal, R., Narayanan, K., Prasad, A., Spanias, A., Sackellares, J.C., & Iasemidis, L.D. (2003). A New Approach Towards Predictability of Epileptic Seizures: KLT Dimension. Biomedical Sciences Instrumentation, 39, 123-128.

Sabesan, S., Narayanan, K., Prasad, A., & Iasemidis, L.D. (2003). Improved Measure of Information Flow in Coupled Non-Linear Systems. The Proceedings of IASTED International Conference on Modeling and Simulation, Palm Springs, USA, 329-333.

Veeramani, B., Narayanan, K., Prasad, A., Iasemidis, L.D. (2003). On the Use of Directed Transfer Function for Nonlinear systems. The Proceedings of IASTED International Conference on Modeling and Simulation, Palm Spring, USA, 270-274.

Venugopal, R., Prasad, A., Narayanan, K., & Iasemidis, L.D. (2003). Nonlinear Noise Reduction and Predictability of Epileptic Seizures. The Proceedings of IASTED International Conference on Modeling and Simulation, Palm Springs, USA, 240-245.

Narayanan, K., Weber, D.J., He, J., Prasad, A., & Iasemidis, L.D. (2002). Analysis of Neuronal Interactions during Adaptation and Learning in Motor Control of Primates: A Model Independent Approach Using Information Theory. Proceedings of the Second Joint EMBS/BMES Conference, Houston, TX, USA, Oct. 23- 26, 2552-2553.

Narayanan, K., Govindan, R.B., Ramasubba Reddy, M., & Gopinthan, M.S. (1997). Dynamics of Cardiac System through Unstable Periodic Orbits. Proceedings of 19th International Conference - International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL. Oct.30 - Nov. 2, 2019-2021.

JOURNAL PUBLICATIONS UNDER PEER-REVIEW (* indicates that Dr. Krishnamurthi is PI of the study)

Larkey, L., Kim, W., James, D., Kishida, M., Vizcaino, M., Huberty, J., Krishnamurthi, N. (under review). Mind-body and Psychosocial Interventions may Similarly Affect Heart Rate Variability Patterns in Cancer Recovery: Implications for a Mechanism of Symptom Improvement. Integrated Cancer Therapies

Second Senior Author of the Study

JOURNAL PUBLICATIONS UNDER PREPARATION (* indicates that Dr. Krishnamurthi is PI of the study)

*Krishnamurthi, N., ‡Baskaran, D., ‡Niveditha, M., Mahant, P., Ospina, M.C., & Abbas, J.J. Effects of Real-Time Feedback Training on Gait and Posture in Parkinson’s Disease – A Pilot Study.

*Krishnamurthi, N., ‡Balasubramanian, S., & Abbas, J.J. Characterization of Changes in Balance Control Due to Aging And Parkinson’s Disease Using Dynamic Posture Shifts.

*Krishnamurthi, N., Dhall, R., Lieberman, A., & Deep, A. Effects of Low-Frequency Stimulation on Gait and Balance in People with PD with Deep Brain Stimulation System.

PEER-REVIEWED BOOK CHAPTERS

Sabesan, S., Narayanan, K., Prasad, A., Iasemidis, L.D., Spanias, A., & Tsakalis, K. (2007). Information Flow in Coupled Nonlinear Systems: Application to the Epileptic Human Brain, In P. Pardalos, V. Boginski, A. Vazacopoulos (Eds.), Data Mining in Biomedicine, Optimization and its Applications Series, pp. 483-504. Springer.

Govindan, R.B., Narayanan, K., Gopinathan, M.S., & Pradhan, N. (2000). Unstable Periodic Orbit Spectra of Theoretical and Experimental Dynamical Systems. In S. K. Malik, M. K. Chandrashekharan & N. Pradhan (Eds.) Nonlinear Phenomena In Physical and Biological Sciences, pp. 153-194.

Govindan, R.B., Narayanan, K., & Gopinathan, M.S., Pradhan, N., Sreenivasan, R., & Dwivedi, P. (1999). The Spectrum of Unstable Periodic Orbits of the Human Brain. In R. Sreenivasan, N. Pradhan & P.E. Rapp (Eds.) Nonlinear Dynamics and Brain Functioning, pp. 345-377. Nova Science Publishers.

REFEREED ABSTRACTS (* indicates that Dr. Krishnamurthi is PI of the study)

‡Muthukrishnan, N., Abbas, J.J., Turaga, P., Ingalls, T., & *Krishnamurthi, N. (2019). Gait and Balance Monitoring using Wearable Technology for Real-Time Feedback in Parkinson’s Disease. Society for Neuroscience Conference, October 19-23, Chicago, IL.

*Krishnamurthi, N., ‡Baskaran, D., Parikh, S., Venugopal, V., ‡Muthukrishnan, N., Driver- Dunckley, E., Mahant, P., Ospina, M.C., & Abbas, J.J. (2019). Real-Time Feedback during Treadmill Training for Individuals with Parkinson’s Disease. Society for Neuroscience Conference, October 19-23, Chicago, IL.

‡Baskaran, D., *Krishnamurthi, N., Mahant, P., Ospina, M.C., & Abbas, J.J. (2017). Real-Time Feedback Training to Improve Gait and Posture in Parkinson’s Disease. Biomedical Engineering Society Annual Meeting, October 11-14, Phoenix, AZ.

*Krishnamurthi, N., ‡Herrera, P., Mahant, P., Honeycutt, C., & Abbas J.J. (2016). Effects of Split-Belt Treadmill Training on Gait in People with Parkinson’s Disease. Annual Meeting of American Society of Neurorehabilitation, November 10-11, San Diego, CA.

*Krishnamurthi, N., ‡Jellish, J., Ingalls, T., Mahant, P., Samanta, J., Ospina, M.C., & Abbas, J.J. (2016). Real-Time Feedback Improves Gait and Posture in Parkinson’s Disease. 9th World Congress for Neurorehabilitation, May 10-13, Philadelphia, PA.

Deep. A., Lieberman, A., Dhall, R., Lockhart, T., Shafer, S., Frames, C., Tateuchi, N., Simpson, E., McCauley, M., Krishnamurthi, N., & Syed, S. (2016). Measurement of Effect of Variable Deep Brain Stimulation (DBS) Frequencies on Static Postural Control in Parkinson’s Disease (PD) Patients with Bilateral STN Or Gpi Stimulators by Employing Force Plate, Movement Disorders, 31, S20-S21.

Deep, A., Lieberman, A., Dhall, R., Lockhart, T., Frames, C., Shafer, S., Tateuchi, N., Simpson, E., McCauley, M., & *Krishnamurthi, N. (2016). Comparison of Effect of Variable Deep Brain Stimulation (DBS) Frequencies on Gait And Balance in Parkinson’s Disease Patients with Either Bilateral Gpi Or STN Stimulators Employing Wearable Wireless Sensors. Movement Disorders, 31, S23-S24.

‡Balasubramanian, S., Abbas, J.J., & *Krishnamurthi, N. (2016). Characterization of Balance Control Through Dynamic Posture Shifts. Southern Biomedical Engineering Conference, March 11-13, Shreveport, LA.

Deep, A., Dhall, R., Lieberman, A., & *Krishnamurthi, N. (2015). To Test the Effect of Deep Brain Stimulation (DBS) Frequencies on Gait Abnormalities in Parkinson’s Disease. Movement Disorders, 30, S216-216.

A10

Deep, A., Lieberman, A., Dhall, R., Tran, A., Liu, M.J., Saha, K., Salins, N., Sadreddin, A., Moguel-Cobos, G., Shi, J., Karis, J., & Krishnamurthi, N. (2014). To Study Finger Displacement in Parkinson’s Disease Patients with And without Dementia. Annals of Neurology, 76, S40-S40, Supplement 18.

A11

Lieberman, A., Deep, A., Dhall, R., Krishnamurthi, N., Salins, N., & Pan, D. (2014). An Investigation of Recurrent Falls in Parkinson’s Disease. Annals of Neurology, 76, S43-S43, Supplement 18.

A12

Deep, A., Lieberman, A., Dhall, R., Shi, J., Tran, A., Liu, M.J., Saha, K., Salins, N., Sadreddin, A., Moguel-Cobos, G., Karis, J., & Krishnamurthi, N. (2014). Finger Displacement: A Test to Predict Dementia in Parkinson’s Patient. Movement Disorders, 29 (10), E7-E8.

A13

Dhall, R., *Krishnamurthi, N., Deep, A., Lieberman, A., Wilhelm, K., & ‡Akhtar, S. (2014). Gait Abnormalities in Parkinson’s Disease: Does Subthalamic Nucleus or Globus Pallidus Internus Variable Frequency Deep Brain Stimulation Help? Movement Disorders, 29 (10), E8-E8.

A14

*Krishnamurthi, N., Dhall, R., ‡Akhtar, S., & Wilhelm, K. (2013). Effects of Low-Frequency Deep Brain Stimulation of the Subthalamic Nucleus or Globus Pallidus Internus on Gait in Parkinson’s Disease. 3rd World Parkinson Congress, October 1-4, Montreal, Canada.

A15

Krishnamurthi, N., Murphey, C., & Driver-Dunckley, E. (2013). Comprehensive Dance-Based Movement Program Improves Mobility in Parkinson’s Disease. 3rd World Parkinson Congress, October 1-4, Montreal, Canada.

A16

Dhall, R., Krishnamurthi, N., Lieberman, A., & Wilhelm, K. (2013). Evaluation of Impaired Integration of Proprioception and Motor Information in Parkinson’s Disease Using Extremity Drift in the Absence of Visual Input. 3rd World Parkinson Congress, October 1-4, Montreal, Canada.

A17

*Krishnamurthi, N., Shill, H., O’Donnell, D., Lieberman, A., Mahant, P., Samanta, J. & Abbas, J.J. (2013). Effects of Polestriding on Gait in Parkinson’s Disease. 3rd World Parkinson Congress, October 1-4, Montreal, Canada.

A18

*Krishnamurthi, N., Shill, H., Stovall, J., O’Donnell, D., Calabrese, E., Lieberman, A., Mahant, P., Samanta, J., &. Abbas, J.J. (2013). Effects of Polestriding Training on Gait in Parkinson’ Disease. 29th Southern Biomedical Engineering Conference, May 3-5, Miami, FL (platform presentation).

A19

Lieberman, A., Dhanani, S., Dhall, R., Santiago, A., Krishnamurthi, N., & Pan, D. (2013). Distinguishing the Tremor of Parkinson’s Disease from Essential Tremor: Finger Displacement. Movement Disorders, 28 (10), E4-E4.

A20

Dhall, R., Krishnamurthi, N., Lieberman, A., Dhanani, S., & Pan, D. (2013). Why Levodopa May Increase Falls in Parkinson’s Disease. 65th Annual Meeting of the American Academy of Neurology, March 16-23, San Diego, CA.

A21

Lieberman, A., Krishnamurthi, N., Dhall, R., Santiago, A., Dhanani, S., & Pan, D. (2013). A Simple Means of Distinguishing the Tremor of Parkinson Disease from Essential Tremor: The Alien Finger. 65th Annual Meeting of the American Academy of Neurology, March 16-23, San Diego, CA.

A22

Lieberman, A., Krishnamurthi, N., Dhall, R., Dhanani, S., & Pan, D. (2013). Identifying Risk Factors for Falls in Parkinson’s Disease Using the UPDRS. 65th Annual Meeting of the American Academy of Neurology, March 16-23, San Diego, CA.

A23

*Krishnamurthi, N., Fife, T., & Shi, J. (2013). Simple Computerized Quantification of Gait Measures Before and After CSF Removal in Evaluation of NPH. 65th Annual Meeting of the American Academy of Neurology, March 16-23, San Diego, CA.

A24

Lieberman, A., Krishnamurthi, N., Santiago, A., Dhall, R., Moguel-Cobos, G., Sadreddin, A., Husain, S., Salins, N., Pan, D., & Dhanani, S. (2012). Is Difficulty with Balance Different Difficulty Walking in Parkinson’s Disease. 64th Annual Meeting of the American Academy of Neurology, April 21-28, New Orleans, LA.

A25

Husain, S., Krishnamurthi, N., Santiago, A., Dhall, R., Moguel-Cobos, G., Sadreddin, A., Salins, N., Pan, D., Lieberman, A., & Dhanani, S. (2012). The Value of the Barrow Neurological Institute Balance Scale in Prediction Falls. 64th Annual Meeting of the American Academy of Neurology, April 21-28, New Orleans, LA.

A26

Salins, N., Krishnamurthi, N., Santiago, A., Dhall, R., Moguel-Cobos, G., Sadreddin, A., Husain, S., Lieberman, A., Pan, D., & Dhanani, S. (2012). Gait and Posture Control Impairments Predict Falls in Parkinson’s Disease. 64th Annual Meeting of the American Academy of Neurology, April 21-28, New Orleans, LA.

A27

Lieberman, A., Krishnamurthi, N., Santiago, A., Dhall, R., Moguel-Cobos, G., Sadreddin, A., Salins, N., Pan, D., & Dhanani, S. (2012). Effects of Bradykinesia and Hypokinesia on Falls in Parkinson’s Disease. 64th Annual Meeting of the American Academy of Neurology, April 21-28, New Orleans, LA.

A28

Lynskey, J., Clark, K., Whitefield, K., Stovall, J., Narayanan, K., Samanta, J., Mahant, P., Bosch, P., & Abbas, J.J. (2012). The Feasibility and Acute Effects of Polestriding in Individuals with Parkinson’s Disease Who Exhibit Freezing of Gait. Combined Sections Meeting – American Physical Therapy Association, February 8-11, Chicago, IL.

A29

*Krishnamurthi, N., Shill, H., Stovall, J., O’Donnell, D., Mahant, P., Samanta, J., Lieberman, A., & Abbas, J.J. (2011). Polestriding Improves Gait in Parkinson’s Disease. 41st Annual Meeting of Society for Neuroscience, Washington, DC.

A30

*Krishnamurthi, N., Williams, C., Stovall, J., Biemond, A., Raasch, M., & Abbas, J.J. (2011). Electrical Stimulation Training to Improve Orthostatic Tolerance in Spinal Cord Injury. 41st Annual Meeting of Society for Neuroscience, Washington, DC.

A31

Krishnamurthi, N. Conovoloff, A., Mahant, P., Samanta, J. & Abbas, J.J. (2007). Effects of Deep Brain Stimulation Amplitude on Gait in Parkinson’s Disease. 37th Annual Meeting of Society for Neuroscience, November 3-7, San Diego, CA.

A32

Downing, A., Narayanan, K., & Abbas, J.J. (2007). Postural Control of Self-Initiated Weight Shifts in Children and Adults. Annual Conference of American Society for Biomechanics, August 22-25, Stanford, CA. (platform presentation).

A33

Krishnamurthi, N., Mulligan, S., Mahant, P., Samanta, J., & Abbas, J.J. (2006). Deep Brain Stimulation Alters Postural Control in Parkinson’s Disease. 36th Annual Meeting of Society for Neuroscience, October 14-18, Atlanta, GA.

A34

Narayanan, K., Mulligan, S., Mahant, P., Samanta, J., & Abbas, J.J. (2006). Deep Brain Stimulation Effects on Posture Control in Parkinson’s Disease. Movement Disorders, 21 (S13), S115.

A35

Mulligan, S., Narayanan, K., Mahant, P., Samanta, J., & Abbas, J.J. (2005). Effect of Deep Brain Stimulation on Posture Control in Parkinson’s Disease. Movement Disorders, 20 (S10), S141.

A36

Hsiao-Wecksler, E.T., Narayanan, K., Lee, B.S., Laughton, C.A., & Lipsitz, L.A. (2003). Does Tai Chi Affect Postural Sway & Muscle Activity in Older Adults? 27th Annual Meeting of the American Society of Biomechanics, September 25-27, Toledo, OH.

A37

Prasad, A., Narayanan, K., Tsakalis, K., & Iasemidis, L.D. (2003). Hysteresis in Coupled Chaotic Oscillators and Application to Epileptic Seizures. International Nonlinear Sciences Conference on Research and applications in the Life Sciences, February 7-9, Vienna, Austria.

A38

Iasemidis, L.D., Prasad, A., Narayanan, K., Sackellares, J.C., Pardalos, P.M., Shiau, D.S., & Chaovalitwongse, W. (2003) Prediction of Epileptic Seizures by Linear and Nonlinear Methods. International Nonlinear Sciences Conference on Research and applications in the Life Sciences, February 7-9, Vienna, Austria.

A39

Krishnamurthi, N., & Lipsitz, L.A. (2001). Do Resting Cerebral Pressure - Flow Dynamics Predict Cerebral Blood Flow Responses to Orthostatic Stress? Effects of Healthy Aging. Experimental Biology, 31 March - 4 April, Orlando, FL.

ABSTRACTS UNDER REVIEW (* indicates that Dr. Krishnamurthi is PI of the study)

Larkey, L., Krishnamurthi, N., James, D., & Huberty, J. (2020). Preliminary Findings on HRV and Stress Related to Body Fat % in a Tai Chi Easy/Qigong Intervention for Breast Cancer Survivors. 41st Annual Meeting of Society of Behavioral Medicine, April 1-4, San Francisco, CA.

Research Activity

GRANTS FUNDED

Developing a Real-Time Fall Risk Assessment in Parkinson’s Disease by Continuous Monitoring of Free-Living Activities

Center for Innovation in Healthy and Resilient Aging; Arizona State University; $47,000; 01/01/19 – 12/31/20;

This study will identify the abnormal gait patterns in frequent fallers that precede falls/near fall events, if any, and utilize it to develop a classifier to predict an impending fall in real-time.

Role: Principal Investigator

Co-Investigators: Pavan Turaga, PhD; Daniel Peterson, PhD

Wearable Real-Time Feedback System to Improve Gait and Posture in Parkinson’s Disease

National Institutes of Health; National Institute of Nursing Research; R21 grant mechanism; $449,401; 07/01/18 - 06/30/20;

This study is to develop a wearable real-time feedback rehabilitation system, validate the system, and test the feasibility of utilizing the system in people with Parkinson’s disease.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Pavan Turaga, PhD; Todd Ingalls, MM; Michael Belyea, PhD; Holly Shill, MD

Real-time Feedback Training to Improve Gait and Posture in People with Parkinson’s Disease

Arizona State University-Mayo Seed Grant Program; $50,000; 01/01/18 – 06/30/19

To investigate whether regular participation in an exercise program that uses feedback can improve gait patterns and posture during overground walking.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Erica Driver-Dunckley, MD

Continuous Monitoring to Investigate the Effects of Sleep Behavior Disorder on Gait Dysfunction in People with Parkinson’s Disease

Project HoneyBee, Center for Sustainable Health, Arizona State University

09/01/16 – 08/31/17; $27,401;

To investigate the effects of sleep on gait and posture impairments in people with PD.

Role: Principal Investigator

Co-Investigators: Naomi Salins, MD

Long-Term Continuous Monitoring to Characterize the Effects of Deep Brain Stimulation on Gait and Balance Dysfunction in People with Parkinson’s Disease

Project HoneyBee, Center for Sustainable Health, Arizona State University

09/01/15 – 08/31/16; $26,921;

To investigate the effects of subthalamic or globus pallidus internus deep brain stimulation (DBS) on gait in people with PD by obtaining quantitative gait variables continuously for 7 days in their home environment at pre- and 6 months post-DBS. The continuous gait were obtained using wearable sensors.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Padma Mahant, MD; Naomi Salins, MD

Long-Term Gait Monitoring to Improve Patient Selection for Shunt Surgery in Normal Pressure Hydrocephalus (NPH)

Project HoneyBee, Center for Sustainable Health, Arizona State University

09/01/14 – 08/31/15; $7,000

To study the effects of a tap test on gait in people with normal pressure hydrocephalus.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Terry Fife, MD; Rohit Dhall, MD

Effect of Vitamin D3 Supplementation on Dynamic Stability in Community-Dwelling Older Subjects

Abbott; $122,250; 07/01/15 – 06/30/17

Role: Co-Investigator

Principal Investigator: Thurmon Lockhart, PhD

Other Co-Investigators: James Abbas, PhD; Michael Caplan, PhD; Claire Honeycutt, PhD; Corrie Whisner, PhD

Exercise Training in Parkinson’s disease: Neural and Functional Benefits

National Institute of Health; National Institute of Child Health and Human Development; National Center for Medical Rehabilitation Research

09/23/08 – 03/31/13 $495,525

The study investigated the benefits of a physical exercise program, polestriding, in persons with Parkinson’s disease. Specifically, this study quantifies functional benefits and document changes in brain function through the use of 18F-FDG PET imaging techniques.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Wayne Willis, PhD; Holly Shill, MD; Abraham Lieberman, MD; Kewei Chen, PhD; Padma Mahant, MD; Johan Samanta, MD

Exercise Training in Parkinson’s disease: Neural and Functional Benefits (Supplement)

National Institute of Health; National Institute of Child Health and Human Development; National Center for Medical Rehabilitation Research

09/01/2010 - 08/31/2012 $114,116

The goal was to extend the FDG-PET imaging aspect of the parent study to all the 16 participants. This will enable us to obtain more definitive conclusions on the ability of regular exercise training to produce beneficial alterations in brain metabolic activity patterns.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Wayne Willis, PhD; Holly Shill, MD; Abraham Lieberman, MD; Kewei Chen, PhD; Padma Mahant, MD; Johan Samanta, MD

Improving Mobility in Parkinson’s disease: Effects of a Dance-Based Movement Program

Arizona State University – Mayo Seed Grant Program 01/01/2011 – 06/30/2012

$40,000

This study explored the effects of a dance-based movement program called Movement and Motion specifically designed to improve mobility (balance, gait, and range of motion) in people with Parkinson’s disease.

Role: Co-Investigator

Principal Investigator: Claudia Murphey, MA

Other Co-investigator: Erika Driver-Dunckley, MD

Improving Orthostatic Tolerance after Spinal Cord Injury

Paralyzed Veterans of America Research Foundation; Grant Number: 2546; $150,000, 07/01/08 – 06/30/2010

The major goal of this project was to investigate the use of neuromuscular electrical stimulation to alleviate orthostatic hypotension in people with complete spinal cord injury.

Role: Principal Investigator

Co-Investigators: James Abbas, PhD; Denise Campagnolo, MD; Candyce Williams, MD

Courses

2021 Spring

Course Number	Course Title
HCI 554	Outcomes Evaluation
HCI 554	Outcomes Evaluation

2020 Fall

Course Number	Course Title
BME 792	Research
HCI 554	Outcomes Evaluation

2020 Spring

Course Number	Course Title
HCI 554	Outcomes Evaluation

2019 Fall

Course Number	Course Title
BME 792	Research
NUR 617	Foundation in Science

2019 Spring

Course Number	Course Title
HCI 540	Applying Principles of EBP

2018 Fall

Course Number	Course Title
BME 792	Research
NUR 617	Foundation in Science
BME 592	Research

Honors / Awards

Honors and Awards

2017: Arizona State University - Mayo Clinic Seed Grant Award

2016: Project HoneyBee Observational Clinical Trial Award – Year 3

2015: Project HoneyBee Observational Clinical Trial Award – Year 2

2014: Project HoneyBee Observational Clinical Trial Award – Year 1

2010: Arizona State University - Mayo Clinic Seed Grant Award

2010: ARRA Supplement Research Grant Award from National Institutes of Health

2008: Exploratory Research Grant Award from National Institutes of Health

2008: Clinical Study Research Grant Award from Paralyzed Veterans of America

2006: First World Parkinson Congress – Junior Scholarship Award

2001: Neural Control and Autonomic Regulation (NCAR) Young Investigator Award Finalist

2000: Integrated Rehabilitation and Engineering Program Fellowship from Center for Applied Bio Dynamics, Boston University

1999: Max-Planck Institute Visiting Postdoctoral Fellowship, Germany

1995: Senior Research Fellowship from the University Grants commission, India

1993: Junior Research Fellowship from the University Grants commission, India

Professional Associations

Professional Society Memberships

Member: American Society for Neurorehabilitation

Member: IEEE Engineering in Medicine & Biology Society

Graduate Faculties / Mentoring History

*I served as a Co-chair since my adjunct appointment at SBHSE/ASU does not allow me to Chair. But these theses are based on my ideas and I played significant role in the capacity of a Chair.

2017 - Chaitanya Potaraju

Program of Study: PhD Electrical Engineering, Arizona State University

Project Title: The Design and Evaluation of Quantitative Assessment of Human Walking Patterns Based on Bilateral Symmetry

Role: Committee Member

2016 - Stephanie Santiago

Program of Study: DNP College of Nursing and Health Innovation, Arizona State University

Project Title: Continuous Monitoring to Investigate the Effects of Sleep Behavior Disorder on Gait Dysfunction in People with Parkinson’s Disease

Role: Clinical Residency Mentor

2016 - Brandon Bartels, Arianna Moreno, Haley Sivertson, Maria Jose Quezada

Program of Study: Biomedical Engineering Capstone Team Project, School of Biological and Health Systems Engineering, ASU

Project Title: Parkinsonian Gait Visual Feedback System

Role: Co-mentor

2016 - Anirudh Som

Program of Study: PhD Electrical Engineering, Arizona State University

Project Title: Attractor-based descriptors for balance impair assessment

Role: Committee Member

2016 - Qiao Wang

Program of Study: PhD Thesis, Electrical Engineering, Arizona State University

Project Title: Analyzing and Improving human movement quality

Role: Committee Member

2016 - Deepika Baskaran

Program of Study: MS Thesis, SBHSE, Arizona State University

Project Title: Real-time feedback training to improve gait and posture in Parkinson’s disease

Role: Co-chair*

2016 – Amy Kleinhans

Program of Study: DNP College of Nursing and Health Innovation, Arizona State University

Project Title: Long-term continuous monitoring to characterize the effects of deep brain stimulation on gait and balance dysfunction in people with Parkinson’s disease

Role: Clinical Residency Mentor

2016: Payton Herrera

Program of Study: MS Applied Project, SBHSE, Arizona State University

Project Title: Split-belt treadmill training to improve gait in people with Parkinson’s disease

Role: Co-chair*

2016: Anirudh Som

Program of Study: MS Electrical Engineering, Arizona State University

Project Title: Attractor-based descriptors for balance impair assessment

Role: Committee Member

2015 - 2016 David Stinson

Program of Study: PhD College of Nursing and Health Innovation, Arizona State University

Role: Co-chair

2015: Sarah Flores

Program of Study: DNP College of Nursing and Health Innovation, Arizona State University

Project Title: Long-term continuous monitoring to characterize the effects of deep brain stimulation on gait and balance dysfunction in people with Parkinson’s disease

Role: Clinical Residency Mentor

2015 - 2016 Tanya Singh, Miles Parris, Vivian Vuong

Program of Study: Biomedical Engineering Capstone Team Project, School of Biological and Health Systems Engineering, ASU

Project Title: Parkinson Gait

Role: Co-mentor

2015: Vinay Venkataraman

Program of Study: PhD Electrical Engineering, Arizona State University

Project Title: Kinematic and dynamical analysis techniques for human movement analysis

Role: Committee Chair

2015: Zheng Tan

Program of Study: MS Applied Project, SBHSE, Arizona State University

Project Title: Using PPG and ECG signal for continuous cuffless blood pressure measurement

Role: Committee Chair

2014 – 2015: Debra Corley

Program of Study: DNP College of Nursing and Health Innovation, Arizona State University

Project Title: Long-term monitoring to improve patient selection for shunt surgery in normal pressure hydrocephalus

Role: Clinical Residency Mentor

2013 – 2015: Catherine Vuong

Program of Study: PhD SBHSE, Arizona State University

Project Title: Feedback paradigm for rehabilitation of people with Parkinson’s disease

Role: Committee Chair

2012 – 2015: Shaan Akhtar

Program of Study: MD University of Arizona College of Medicine, Phoenix

Project Title: Effects of deep brain stimulation of subthalamic nucleus versus globus pallidus internus on gait and posture in Parkinson’s disease

Role: Thesis Co-Mentor

2012 – 2014: Shruthi Balasubramanian

Program of Study: MS SBHSE, Arizona State University

Project Title: Age related changes in balance and gait

Role: Committee Co-Chair*

2011 – 2014: Jeremy Jellish

Program of Study: MS SBHSE, Arizona State University

Project Title: Real-time feedback to improve posture and gait in Parkinson’s disease

Role: Committee Co-Chair*

2011 – 2013: Alison Conovaloff

Program of Study: PhD SBHSE, Arizona State University

Project Title: The effects of deep brain stimulation amplitude on motor performance in Parkinson’s disease

Role: Committee Member

2010 – 2011: Jeremy Jellish

Program of Study: BS SBHSE, Arizona State University

Project Title: Effects of rowing exercise on seated posture control in individuals with spinal cord injury

Role: Honors Thesis Committee Co-Chair

2010 – 2011: Shravan Sridhar

Program of Study: BS SBHSE, Arizona State University

Project Title: The Effects of Rowing Exercise Therapy on Shoulder Range of Motion and Steadiness in Individuals with Spinal Cord Injury

Role: Honors Thesis Committee Co-Chair

2010 – 2011: John Spanias

Program of Study: BS SBHSE, Arizona State University

Project Title: Stroke Rehabilitation using Functional Electrical Stimulation: Evaluating Algorithms for Adaptive Control of Electrical Stimulation

Role: Honors Thesis Committee Co-Chair

Service

University Service

2015- Member of Standards Committee – Interprofessional Education, College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ

2014, 2015, 2016: Member, PhD Student Selection Committee Member College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ

2014: Member, PhD Student Interview Member, School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ

Invited Reviewer

Grants:

2016: Biomedical Research Foundation of North Louisiana

2014: Veterans Affairs Rehabilitation Research and Development, Small Projects in Rehabilitation Research

2007: American Institute of Biological Sciences

Journals:

2017: PLOS ONE

2016: PLOS ONE

2015: Physica A

2009: Journal of Neural Engineering

2009: Medical Engineering and Physics

2008: Journal of Neurology, Neurosurgery & Psychiatry

2003, 2004, 2008: IEEE Transactions on Biomedical Engineering

2007: IEEE Transactions on Neural Systems and Rehabilitation Engineering

2003: Medical & Biological Engineering and Computing

Conferences:

2017: 39th Annual International IEEE-Engineering in Medicine and Biology Society Conference

2016: 38th Annual International IEEE-Engineering in Medicine and Biology Society Conference

2015: 37th Annual International IEEE-Engineering in Medicine and Biology Society Conference

2014: 36th Annual International IEEE-Engineering in Medicine and Biology Society Conference

Session Chair

Conferences:

2016: Session: Biomedical Signals Acquisition & Processing, 32nd Southern Biomedical Engineering Conference, March 11-13, 2016, Shreveport, LA

Program Committee Member

Conferences:

2016: 32nd Southern Biomedical Engineering Conference, March 11-13, 2016, Shreveport, LA

2014-2015: International Congress on Neurotechnology, Electronics, and Informatics – NEUROTECHNIX 2015

2013: 29th Southern Biomedical Engineering Conference, May 3-5, 2013, Miami, FL

2009-2011: International Conference on Bio-inspired Systems and Signal Processing (BIOSIGNALS)

2008: First International Joint Conference on Biomedical Engineering Systems and

Technologies (BIOSTEC-2008)

Community Service

2015: Awarded a Traditional Neighborhood Program Grant to Chandler City to help neighborhood residents to get free paint for their fence walls ($5,000)

Expertise Areas

Wearable Technologies