Publications
- Borges, C.R; Jarvis, J.; Oran, P.; Nelson, R.W, . Population Studies of Vitamin D Binding Protein Microheterogeneity by Mass Spectrometry Lead to Characterization of its Genotype Dependent O-glycosylation Patterns. J. Proteome Res (2008).
- Niederkofler, E.E., Kiernan, U.A., O’Rear, J., Menon, S., Saghir, S., Protter, A.A., Nelson, R.W., Schellenberger, U. Detection of Endogenous B-type Natriuretic Peptide at Very Low Concentrations in Patients with Heart Failure. Circulation: Heart Failure (2008).
- D Nedelkov, K Tubbs, Randall Nelson. Surface Plasmon Resonance-enabled Mass Spectrometry Arrays. Electrophoresis (2006).
- D Nedelkov, Randall Nelson. Surface Plasmon Resonance Mass Spectrometry for Protein Analysis. Methods Mol Biol (2006).
- K Tubbs, U Kiernan, E Niederkofler, D Nedelkov, A Bieber, Randall Nelson. Development of Recombinant-based Mass Spectrometric Immunoassay with Application to Resistin Profiling. Anal Chem (2006).
- Randall Nelson, U Kiernan, D Nedelkov. The Development of a Multiplex Mass Spectrometric Immunoassay Responsive to Myocardial Infarction. J. Proteome Res (2006).
- U Kiernan, D Nedelkov, E Niederkofler, K Tubbs, Randall Nelson. High-throughput Affinity Mass Spectrometry. Methods Mol Biol (2006).
- U Kiernan, R Addobbati, D Nedelkov, Randall Nelson. Quantitative Multiplexed C-reactive Protein Mass Spectrometric Immunoassay. J Proteome Res (2006).
- D Nedelkov, U Kiernan, E Niederkofler, K Tubbs, Randall Nelson. Investigating Diversity in Human Plasma Proteins. PNAS (2005).
- K Tubbs, U Kiernan, E Niederkofler, D Nedelkov, A Bieber, Randall Nelson. High Throughput Mass Spectrometry-Based Protein Phenotyping: Application to Haptoglobin. J. Proteome Res (2005).
- A Bieber, K Tubbs, Randall Nelson. Metal ligand affinity pipettes and bioreactive alkaline phosphatase probes: Tools for characterization of phosphorylated proteins and peptides. Mol. Cell. Proteomics (2004).
- D Nedelkov, K Tubbs, E Niederkofler, U Kiernan, Randall Nelson. High-throughput comprehensive analysis of human plasma proteins: a step toward population proteomics. Anal. Chem (2004).
- Randall Nelson, D Nedelkov, K Tubbs, U Kiernan. Quantitative Mass Spectrometric Immunoassay of Insulin Like Growth Factor 1. J. Proteome Res (2004).
- U Kiernan, D Nedelkov, A Tubbs, E Niederkofler, Randall Nelson. Proteomic characterization of novel serum amyloid P component variants from human plasma and urine. Proteomics (2004).
- U Kiernan, D Nedelkov, A Tubbs, E Niederkofler, Randall Nelson. Selected expression profiling of full-length proteins and their variants in human plasma. Clin. Proteomics (2004).
- C Flynn, C Brophy, P Komalavilas, D Tessier, J Thresher, E Niederkofler, C Dreiza, Randall Nelson, A Panitch, L Joshi. Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle. FASEB J (2003).
- D Nedelkov, Randall Nelson. Delineating protein-protein interactions via biomolecular interaction analysis-mass spectrometry. J. Mol. Recogn (2003).
- D Nedelkov, Randall Nelson. Design and use of multi-affinity surfaces in biomolecular interaction analysis-mass spectrometry (BIA/MS): a step toward the design of SPR/MS arrays. J. Mol. Recogn (2003).
- D Nedelkov, Randall Nelson. Detection of staphylococal enterotoxin B via biomolecular interaction analysis mass spectrometry. Appl. Environ. Microbiol (2003).
- D Nedelkov, Randall Nelson. Surface plasmon resonance mass spectrometry: recent progress and outlooks. Trends Biotecnol (2003).
- D Nedelkov, Randall Nelson, U Kiernan, E Niederkofler, K Tubbs. Detection of bound and free IGF-1 and IGF-2 in human plasma via biomolecular interaction analysis mass spectrometry. FEBS Lett (2003).
- E Niederkofler, K Tubbs, U Kiernan, D Nedelkov, Randall Nelson. Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins. J. Lipid Res (2003).
- S Wong, Randall Nelson, U Kiernan, E Sahin, P Jannetto, S Gock, J Jentzen. Toxico-proteomics: MALDI-TOF Mass Spectrometric Immunoassay of Carbohydrate Deficient Transferrin for Assessing Chronic Alcohol Abuse. Therapeutic Drug Monitoring (2003).
- U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, E McConnel, Randall Nelson. Comparative urine protein phenotyping using mass spectrometric immunoassay. J. Proteome Res (2003).
- U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, Randall Nelson. Detection of novel truncated forms of human serum amyloid A protein in human plasma. FEBS Lett (2003).
- D Nedelkov, K Tubbs, Randall Nelson. Design of buffer exchange surfaces and sensor chips for Biosensor Chip Mass Spectrometry. Proteomics (2002).
- R Lukas, K Tubbs, A Krivoshein, A Bieber, Randall Nelson. Mass Spectrometry of nicotinic acetylcholine receptors and associated proteins as models for complex transmembrane proteins. Anal. Biochem (2002).
- U Kiernan, D Nedelkov, K Tubbs, E Niederkofler, Randall Nelson. High-throughput analysis of human plasma proteins. Am. Biotech. Lab (2002).
- U Kiernan, J Black, P Williams, Randall Nelson. High-throughput analysis of hemoglobin from neonates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin. Chem (2002).
- U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, Randall Nelson. Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay. Biochem. Biophys. Res. Commun (2002).
- U Kiernan, K Tubbs, K Gruber, D Nedelkov, E Niederkofler, P Williams, Randall Nelson. High-throughput protein characterization using mass spectrometric immunoassay. Anal. Biochem (2002).
- Nedelkov, D (Author) ,Nelson, Randall William (Author) . Biomolecular Interaction Analysis Mass Spectrometry. Mass Spectrometry and hyphenated techniques in neuropeptide research (2002).
- D Nedelkov, Randall Nelson. Analysis of human protein biomarkers via biomolecular interaction analysis mass spectrometry. Am. J. Kid. Dis (2001).
- D Nedelkov, Randall Nelson. Analysis of native proteins from biological fluids by biomolecular interaction analysis mass spectrometry (BIA/MS): exploring the limit of detection, identification of non-specific binding and detection of multi-protein complexes. Biosens. Bioelec (2001).
- D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry. Bull. Chem. Technol. Macedonia (2001).
- D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry: a comprehensive micro-scale proteomics approach. Amer. Lab (2001).
- D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry: a multiplexed proteomics approach. Biopharm (2001).
- D Nedelkov, Randall Nelson. Delineation of in-vivo assembled multi-protein complexes via Biomolecular Interaction Analysis Interaction Mass Spectrometry. Proteomics (2001).
- E Niederkofler, K Tubbs, K Gruber, D Nedelkov, U Kiernan, P Williams, Randall Nelson. Determination of b-2-microglobulin Levels in Plasma using a High Throughput Mass Spectrometric Immunoassay System. Anal. Chem (2001).
- D Nedelkov, A Rasooly, Randall Nelson. Multitoxin biosensor-mass spectrometry analysis: a new approach for rapid, real-time, sensitive analysis of Staphylococcal toxins in food. Int.J. Food Microbiol (2000).
- D Nedelkov, Randall Nelson. Exploring the limit of detection in biomolecular interaction analysis mass spectrometry (BIA/MS): detection of attomole amounts of native proteins present in complex biological mixtures. Anal. Chim. Acta (2000).
- D Nedelkov, Randall Nelson. Practical considerations in BIA/MS: optimizing the biosensor-mass spectrometry interface. J. Mol. Recognit (2000).
- K Tubbs, D Nedelkov, Randall Nelson. Detection and quantification of b-2-microglobulin using mass spectrometric immunoassay (MSIA). Anal. Biochem (2000).
- Randall Nelson, D Nedelkov, K Tubbs. Biomolecular Interaction Analysis Mass Spectrometry. BIA/MS can detect and characterize proteins in complex biological fluids at the low- to subfemtomole level. Anal. Chem (2000).
- Randall Nelson, D Nedelkov, K Tubbs. Biosensor chip mass spectrometry: a chip-based proteomics approach. Electrophoresis (2000).
- Nelson, Randall William (Author) . Update to: Mass spectrometric methods for evaluating point mutations. Polymorphism detection and analysis (2000).
- Bakhtiar, R, Nelson, Randall. Electrospray Ionization and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry: Emerging Technologies in Biomedical Science (Invited review). (2000).
Research Activity
- Nelson,Randall William*. Glycemic and non-glycemic determinants of HbA1c and the identification of novel markers of glycemia. NUS(6/1/2013 - 7/31/2015).
- Nelson,Randall William*. Next Generation Clinical Mass Spectrometry Platform. VIC Instruments(9/1/2012 - 8/31/2015).
- Nelson,Randall William*. Hitachi Collaboration: MSIA of Small Molecules. HITACHI LTD(2/27/2012 - 2/26/2013).
- Nelson,Randall William*, Borges,Chad Randolph. Team Approach to Translate Novel Biomarkers for Diabetes. HHS-NIH-NIDDK(8/5/2011 - 7/31/2016).
- Nelson,Randall William*. Characterizing HDL Heterogeneity in T2DM Patients. NUS(3/15/2011 - 3/31/2014).
- Nelson,Randall William*. Mass spectrometric immumoassays for lung cancer. TGen(3/1/2011 - 8/31/2012).
- Nelson,Randall William*, Borges,Chad Randolph. Novel biomarkers for myocardial infarction based on protein heterogeneity. (3/1/2010 - 12/31/2015).
- Nelson,Randall William*, Borges,Chad Randolph. Population-Based Proteomic Investigation of Type 2 Diabetes Mellitus. HHS-NIH-NIDDK(3/1/2010 - 2/29/2016).
- Nelson,Randall William*, Greenes,Robert, Kumar,Sudhir, Mobley,Michael J, Mobley,Michael J. Team Approach to Translate Novel Biomarkers for Diabetes. HHS-NIH-NIDDK(7/1/2009 - 6/30/2011).
- Borges,Chad Randolph*, Nelson,Randall William, Nelson,Randall William. Site-Specific Analysis of Human Cysteine Sulfenic Acid Protein Modifications. HHS-NIH-NCRR(12/1/2007 - 11/30/2010).
Presentations
- R. Nelson. Population Based Proteomics Studies of Type 2 Diabetes. Symposium on Human Variation: A Driver of Personalized Medicine (Jan 2009).
- R. Nelson. Mapping Protein Microheterogeneity: Applications in the Development of Biomarkers for Type 2 Diabetes. Mass Spectrometry: Applications in the Clinical Laboratory (Nov 2008).
- R. Nelson. Mass Spectrometric Immunoassay in Biomarker Development. 6th CHI Conference on Protein Biomarkers (Oct 2008).
- R. Nelson. Arrays in Mass Spectrometry. 35th Federation of Analytical Chemistry and Spectroscopy Societies (Oct 2008).
- R. Nelson. Mapping Protein Microheterogeneity: Applications in the Development of Biomarkers for Type 2 Diabetes. Rocky Mountain Conference on Analytical Chemistry (Jul 2008).
- R. Nelson. Mapping Human Protein Microheterogeneity: Implications for Clinical Diagnostics. US Human Proteome Organization (Mar 2008).
- R. Nelson. The Use of Mass Spectrometric Immunoassay in the Study of Disease. Asilomar Conference on Mass Spectrometry (Sep 2007).
- R. Nelson. Addressing Microheterogeneity in Human Plasma Proteomics. G.O.T Summit (Apr 2007).
- R. Nelson. Addressing Microheterogeneity in Human Plasma Proteomics. The Mayo Clinic (Rochester) (Apr 2007).
- R. W. Nelson. High Throughput Mass Spectrometric Immunoassays in Human Plasma Profiling and Targeted Protein Analysis. The Scripps Research Institute (Feb 2007).
- Kiernan, U, Nedelkov, D, Nelson, Randall. Biomarker Identification and Validation with Targeted Cardiac Population Proteomics. The 53rd ASMS Conference on Mass Spectrometry and Allied Topics (Jun 2005).
- Nelson, Randall. Investigating Diversity in Plasma Proteins. CHI Beyond Genome: The 9th Annual Proteomics Applications in Therapeutic and Diagnostic Developments (Jun 2005).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. 2005 AAPS National Biotechnology Conference (Jun 2005).
- Niederkofler, E, Nedelkov, D, Kiernan, U, Tubbs, K, Nelson, Randall. Detection of Detrimental Levels of the Biotoxin Staphylococcal Enterotoxin B by Affinity Mass Spectrometry. The 53rd ASMS Conference on Mass Spectrometry and Allied Topics (Jun 2005).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. (Apr 2005).
- Nelson, Randall, Nedelkov, D, Kiernan, U, Niederkofler, E, Tubbs, K. Investigating Protein Diversity in Human Populations. US HUPO-2005 (Mar 2005).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. The University of Manitoba (Nov 2004).
- Nelson, Randall. Protein Chips Linked to Mass Spectrometry. The 29th FEBS Congress (Jun 2004).
- Nelson, Randall, Nedelkov, D, Kiernan, U, Niederkofler, E, Tubbs, K. Population Proteomics: Addressing Diversity in Human Proteins. The 52nd ASMS conference on Mass Spectrometry and Allied Topics (May 2004).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. Genentech (May 2004).
- Bieber, A, Nelson, Randall, Tubbs, K, Nedelkov, D, Niederkofler, E, Kiernan, U. Directed Mass Spectrometry-Based Approaches for Characterization of Protein Phosphorylation. The 52nd ASMS conference on Mass Spectrometry and Allied Topics (May 2004).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. Ortho Clinical Diagnostics (Mar 2004).
- Nelson, Randall. Population Proteomics: Addressing Diversity in Human Proteins. Amgen (Jan 2004).
- Nelson, Randall. Protein Phenotyping using Mass Spectrometric Immunoassay. The 226th National ACS Meeting (Sep 2003).
- Nelson, Randall. Adventures in Creating and Arizona Biotech Startup. Arizona Bioindustry Association (Aug 2003).
- Kiernan, U, Nedelkov, D, Tubbs, K, Niederkofler, E, McConnell, E, Nelson, Randall. Phenotypic Characterization of Human Urine Proteins Using Mass Spectrometric Immunoassay. The 51st ASMS conference on Mass Spectrometry and Allied Topics (Jun 2003).
- Nedelkov, D, Rasooly, A, Nelson, Randall. Mass spectrometry based immunoassays for detection of biological pathogens and warfare agents. The 51st ASMS conference on Mass Spectrometry and Allied Topics (Jun 2003).
- Nelson, Randall. Measuring the Chemistry of Life, Discussion Leader, Connecticut College. Gordon Research Conference on Analytical Chemistry (Jun 2003).
- Niederkofler, E, Nedelkov, D, Tubbs, K, Kiernan, U, Nelson, Randall. Mass Spectrometry Based Immunoassays for the Detection of Cardiac Biomarkers. The 51st ASMS conference on Mass Spectrometry and Allied Topics (Jun 2003).
- Nelson, Randall. High-Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. CHI Molecular Medicine 2003 (Mar 2003).
- Nelson, Randall. High Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. Labautomation 2003 (Feb 2003).
- Nelson, Randall. High Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. HPCE2003 (Jan 2003).
- Nelson, Randall, Kiernan, U, Niederkofler, E, Tubbs, K, Nedelkov, D. High-Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. HPCE 2003, 16th International Symposium on Microscale Separations and Analysis (Jan 2003).
- Nelson, Randall. Protein Characterization using Affinity Isolation Mass Spectrometry. Desorption 2002 (Sep 2002).
- Nelson, Randall. Protein Characterization using Affinity Isolation Mass Spectrometry. IFPAC/BIO 2002 (Apr 2002).
- Nelson, Randall. Protein Characterization using Affinity Isolation Mass Spectrometry. 222nd National ACS Meeting (Aug 2001).
- Kiernan, U, Tubbs, K, Niederkofler, E, Nedelkov, D, Williams, P, Nelson, Randall. High-Throughput Integrated Assay via Combination of Mass Spectrometric Immunoassay, Bioreactive Probes and Parallel Robotic Processing. The 49th ASMS conference on Mass Spectrometry and Allied Topics (May 2001).
- Niederkofler, E, Kiernan, U, Nedelkov, D, Tubbs, K, Gruber, K, Williams, P, Nelson, Randall. Quantification of Human Plasma Proteins via Integration of High Throughput Mass Spectrometric Immunoassay System and Functional MALDI targets. The 49th ASMS conference on Mass Spectrometry and Allied Topics (May 2001).
- Nelson, Randall. High-Throughput Protein Characterization using Mass Spectrometric Immunoassay (MSIA). 4th IBC Conference on Proteomics (Mar 2001).
- Nelson, Randall, Nedelkov, D. Innovations in Proteome Analysis: Biomolecular Interaction Analysis Mass Spectrometry. ABRF 2001 (Feb 2001).
- Nelson, Randall, Nedelkov, D. The use of Biomolecular Interaction Analysis Mass Spectrometry (BIA/MS) in the Analysis of Complex Biological Mixtures. HPCE 2001, 14th International Symposium on Microscale Separations and Analysis (Jan 2001).
- Nelson, Randall. The use of Biomolecular Interaction Analysis Mass Spectrometry (BIA/MS) in the Analysis of Complex Biological Mixtures. HPCE2001 (Jan 2001).
- Nelson, Randall, Tubbs, K, Nedelkov, Dobrin. Characterization of Blood Proteins using Mass Spectrometric Immunoassay in Combination with Enzymatically-active MALDI-TOF Targets. The 48th ASMS conference on Mass Spectrometry and Allied Topics (Jun 2000).
- Tubbs, K, Nedelkov, D, Nelson, Randall. Detection and Quantitation of b-2-microglobulin using Mass Spectrometric Immunoassay (MSIA). The 48th ASMS conference on Mass Spectrometry and Allied Topics (Jun 2000).
- Nelson, Randall, Nedelkov, D, Tubbs, K. Detection of low- to sub-femtomole amounts of proteins using Biosensor Chip Mass Spectrometry. The 6th World Congress on Biosensors (May 2000).
- Nelson, Randall. Biomolecular Interaction Analysis Mass Spectrometry (BIA/MS). Labautomation 2000 (Jan 2000).
Service
- NIH study section, Cancer Molecular Pathobiology Study Section, REVIEWER (1998 - Present)
- NIH study section, Center for Scientific Review Special Emphasis Panel, REVIEWER (1998 - Present)
- NIH study section, National Cancer Institute Special Emphasis Panel, REVIEWER (1998 - Present)
- NIH study section, National Institute of Allergy and Infectious Diseases Special Emphasis Panel, REVIEWER (1998 - Present)
- NIH study section, National Institute of Biomedical Imaging and Bioengineering Panel, REVIEWER (1998 - Present)
- NIH study section, National Institute of Environmental Health Sciences Special Emphasis Panel, REVIEWER (1998 - Present)