Jessica Weaver is an assistant professor in the School of Biological and Health Systems Engineering. Her expertise lies in integrating biomaterials, drug delivery, and tissue and immune engineering for the development of functional and immune-protected tissue and cell grafts. Her research focuses on developing safe, translatable technologies with long-term efficacy to widen the applicability of cell therapies to broad patient populations through the elimination of chronic immunosuppression.
Navarro-Requena, C, Weaver, JD, Clark, A, Clift, D, Perez-Amodio, S, Castano, O, Zhou, D, García, AJ, Engel, E, PEG Hydrogel Containing Calcium-Releasing Particles and Mesenchymal Stromal Cells Promote Vessel Maturation, Acta Biomaterialia, 67, 53-65 (2018).
Weaver, JD, Headen, DM, Aquart, J, Johnson, CT, Shea, LD, Shirwan, H, García, AJ, Vasculogenic Hydrogel Enhances Marginal Islet Mass Engraftment and Function in Extrahepatic Transplant Sites, Science Advances, 3 (6), e1700184 (2017).
Moulisova, V, Gonzalez-Garcia, C, Cantini, M, Rodrigo-Navarro, A, Weaver, JD, Costell, M, Sabater I Serra, R, Dalby, MJ, Garcia, AJ, Salmeron-Sanchez, M, Engineered Microenvironments for Synergistic VEGF-Integrin Signaling During Vascularization, Biomaterials, 126, 61-74 (2017).
Jiang, K, Weaver, JD, Li, Y, Chen, X, Liang, L, Stabler, CL, Local Release of Dexamethasone from Macroporous Scaffolds Accelerates Islet Transplant Engraftment by Promotion of Anti-Inflammatory M2 Macrophages, Biomaterials, 114, 71-81 (2017).
Weaver, JD, Song, Y., Pileggi, A, Ricordi, C, Buchwald, P, Stabler, CL, Controlled Release of Glucocorticoids from Organosilicone Constructs for Local Modulation of Inflammation in an Islet Transplant Site, Tissue Engineering Part A, 21 (15-16), 2250-2261 (2015).
Buchwald P, Cechin SR, Weaver JD and Stabler CL, Experimental Evaluation and Computational Modeling of the Effects of Encapsulation on the Time-Profile of Glucose-Stimulated Insulin Release of Pancreatic Islets, BioMedical Engineering OnLine, 14(28), 1-14 (2015).
Weaver, JD, and Stabler, CL, Antioxidant Cerium Oxide Nanoparticle Hydrogels for Cellular Encapsulation, Acta Biomaterialia, 16, 136-144 (2015).
Song, Y, Margolles-Clark, E., Fraker, CA, Weaver, JD, Ricordi, C., Pileggi, A., Stabler, CL, and Buchwald, P., Feasibility of Localized Immunosuppression: 3. Preliminary Evaluation of Organosilicone Constructs Designed for Sustained Drug Release in a Cell Transplant Environment Using Dexamethasone, Pharmazie, 67, 394-399 (2012).
