Ana Cristina Roginski

Postdoctoral Research Scholar, Biodesign Center for Health Through Microbiomes

Postdoctoral Research Scholar, Health Through Microbiomes Researchers

aroginsk@asu.edu

727 E Tyler Street Rm A324B The Biodesign Institute A Tempe, AZ 85287-5701
Mail code: 5701

Campus: Tempe
‌

Education

2022 - Present. Postdoctoral Immunology Arizona State University

2018 - 2022 Ph.D. Biochemistry Universidade Federal do Rio Grande do Sul (Brazil)

2012 - 2018 B.Sc. Pharmacy URI-Campus Erechim (Brazil)

Curriculum Vitae

Research Website URL

https://pubmed.ncbi.nlm.nih.gov/?term=Roginski%20AC%20

Google Scholar URL

https://scholar.google.com/citations?user=Gh2AtfIAAAAJ&hl=en

Research Group

Florsheim Lab

Publications

Experimental evidence that maleic acid markedly compromises glutamate oxidation through inhibition of glutamate dehydrogenase and α-ketoglutarate dehydrogenase activities in kidney of developing rats. Roginski, AC; Cecatto, C; Wajner, SM; Camera, FDM; Castilho, RF; Wajner, M; Amaral, AU. Molecular and Cellular Biochemistry. 2019 Apr 29. doi: 10.1007/s11010-019-03534-7.
Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy. Cecatto, C; Amaral, AU; Roginski, AC; Castilho, RF; Wajner, M. Toxicology in Vitro. 2020 Feb. doi: 10.1016/j.tiv.2019.104665.
Disturbance of bioenergetics and calcium homeostasis provoked by metabolites accumulating in propionic acidemia in heart mitochondria of developing rats. Roginski, AC; Wajner, A; Cecatto, C; Wajner, SM; Castilho, RF; Wajner, M; Amaral, AU. BBA-Molecular Basis of Disease. 2020 May 1. doi: 10.1016/j.bbadis.2020.165682
Differential age-dependent mitochondrial dysfunction, oxidative stress and apoptosis induced by neonatal hypoxia-ischemia in the immature rat brain. Odorcyk, FK; Ribeiro, RT; Roginski, AC; Duran-Carabali, LE; Couto-Pereira, N; Wajner, M; Dalmaz, C; Netto, CA. Molecular Neurobiology. 2021 Jan 8. doi: 10.1007/s12035-020-02261-1.
Ethylmalonic acid impairs bioenergetics by disturbing succinate and glutamate oxidation and induces mitochondrial permeability transition pore opening in rat cerebellum. Alvorcem, LM; Britto, R; Cecatto, C; Roginski, AC; Rohden, F; Scholla, JN; Gumaa, FCR; Figueiro, F; Amaral, AU; Zanatta, G; Seminotti, B; Wajner, M; Leipnitz, G. Journal of Neurochemistry. 2021 Apr 10. doi: 10.1111/jnc.15363.
S-adenosylmethionine induces mitochondrial dysfunction, permeability transition pore opening and redox imbalance in subcellular preparations of rat liver. Seminotti, B; Roginski, AC; Zanatta, Â ; Amaral, AU; Fernandes, T; Spannenberger, KP; Da Silva, LHR; Ribeiro, RT; Leipnitz, G; Wajner, M. Journal of Bioenergetics and Biomembranes. 2021 Aug 04. doi: https://doi.org/10.1007/s10863-021-09914-3.
Ribeiro, RT; Roginski, ACR; Marschner, RA; Wajner, SM; Castilho, RF; Amaral, AU; Wajner, M. Disruption of mitochondrial bioenergetics, calcium retention capacity and cell viability caused by D-2-hydroxyglutaric acid in the heart. BIOCHIMIE, v. 22, p. 1-36, 2022. doi: 10.1016/j.biochi.2022.11.004
Vizuete, AFK; Froes, F; Seady, M; Zanotto, C; Bobermin, LD; Roginski, AC; Wajner, M; Quincozes-Santos, A; Gonlcalves, CA. Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway. Journal of Neuroinflammation, v. 19, p. 1-23, 2022. doi: 10.1186/s12974-022-02612-w
Roginski, AC; Zemniacak, ÂB; Marschner, RA; Wajner, SM; Ribeiro, RT; Wajner, M; Amaral, AU. Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney. Journal of Bioenergetics and Biomembranes, v. 54, p. 203-213, 2022. doi:10.1007/s10863-022-09945-4
Zemniaçak ÂB, Roginski AC, Ribeiro RT, et al. Disruption of mitochondrial bioenergetics and calcium homeostasis by phytanic acid in the heart: Potential relevance for the cardiomyopathy in Refsum disease [published online ahead of print, 2023 Feb 20]. Biochim Biophys Acta Bioenerg. 2023; 1864(2):148961. doi:10.1016/j.bbabio.2023.148961
Marschner RA, Roginski AC, Ribeiro RT, et al. Uncovering actions of type 3 deiodinase in the metabolic dysfunction-associated fatty liver disease (MAFLD). Cells. 2023; 12(7):1022. doi: 10.3390/cells12071022.
Brondani M, Roginski AC, Ribeiro RT, et al. Mitochondrial dysfunction, oxidative stress, ER stress ad mitochondria-ER crosstalk alterations in a chemical rat model of Huntington's disease: Potential benefits of bezafibrate. Toxicol Lett. 2023; 381:48-59. doi: 10.1016/j.toxlet.2023.04.011

Expertise Areas

Biochemistry

Metabolism