Jui-Heng (Henry) Tseng, a molecular and cellular neuroscientist, aims to unravel how normal aging and age-related risk factors lead to neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Even though aging is the primary risk factor for most neurodegenerative diseases, the mechanisms by which aging contributes to changes in the brain remain poorly understood. Employing a multidisciplinary approach, starting at the protein level and progressing towards more relevant animal models, Henry's goal is to understand how aging triggers pathological protein aggregation and consequently nerve cell death, which are both commonly observed in diseased brains. As the cases of AD and PD have been growing rapidly, he also hopes to develop novel therapeutic strategies to confront these devastating diseases.