Uwe Weierstall's research focuses on developing methods for structure determination of biomolecules with X-ray free electron laser (XFEL) sources. These X-ray sources produce very high intensity pulses of X-rays - compared to a regular 3rd generation synchrotron, the number of photons/second is larger by a factor of 10 billion and concentrated into a few femtoseconds. This increase in intensity allows structure determination from much smaller protein crystallites then the ones used in conventional protein crystallography and may even allow single particle structure analysis at high resolution from identical particles (e.g. viruses) where crystals cannot be grown. Professor Weierstall has been involved in XFEL science and the development of liquid jet sample delivery systems since the first XFEL experiments in 2008 at the Linac Coherent Light Source (LCLS).
Ph.D. Physics, Institute of Applied Physics, University of Tübingen, Germany 1994
Diplom in Physics, Institute of Applied Physics, University of Tübingen, Germany 1989