Jordan Yaron

2024

• Yaron JR*, Bakkaloglu S, Macko S, Rhodes S, Norvor-Davis S, Rege K. Inflammasome Modulation with P2X7 Inhibitor A438079-loaded Dressings for Diabetic Wound Healing. Accepted. (*Co/Corresponding Author)
• Ghosh D†, Yaron JR†, Abedin MR, Godeshala S, Kumar S, Kilbourne J, Berthiaume F, Rege K. Bioactive Nanomaterials Kickstart Early Repair Processes and Potentiate Temporally Modulated Healing of Healthy and Diabetic Wounds. Accepted. (†Equal Contributions)
• Yaron JR*, Gosangi M, Pallod S, Rege K*. In situ Light-activated Materials for Skin Wound Healing and Repair: A Narrative Review. Bioengineering & Translational Medicine. In Press. (*Co/Corresponding Author)

2023

• Inamdar S, Suresh AP, Mangal JL, Ng ND, Sundem A, Behbahani HS, Rubino Jr TE, Yaron JR, Khodaei T, Green M, Curtis M, Acharya AP (2023). Succinate in the tumor microenvironment affects tumor growth and modulates tumor associated macrophages. Biomaterials. 301. 122292
• Inamdar S, Suresh AP, Mangal JL, Ng ND, Sundem A, Wu C, Lintecum K, Thumsi A, Khodaei T, Halim M, Appel N, Jaggarapu MMCS, Esrafili A, Yaron JR, Curtis M, Acharya AP (2023). Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice. Nature Communications. 14(1), 5333.
• Inamdar S, Suresh AP, Mangal JL, Ng ND, Sundem A, Behbahani HS, Rubino Jr TE, Shi X, Loa ST, Yaron JR, Hitosugi T, Green M, Gu H, Curtis M, Acharya AP (2023). Succinate based polymers drive immunometabolism in dendritic cells to generate cancer immunotherapy. Journal of Controlled Release. 358, 541-554.
• Jaggarapu MMCS, Ghosh D, Johnston T, Yaron JR, Mangal JL, Inamdar S, Gosangi M, Rege, K, Acharya AP (2023). Alpha-ketoglutaric acid based polymeric particles for cutaneous wound healing. Journal of Biomedical Materials Research Part A. 1-7.
• Ghosh D, Salinas CM, Pallod S, Roberts J, Makin IRS, Yaron JR, Witte RS, Rege K (2022). Temporal evaluation of efficacy and quality of tissue repair upon laser‐activated sealing. Bioengineering & Translational Medicine. 8(2). e10412

2022

• Zanetti IR, Burgin M, Zhang L, Yeh S, Ambadapadi S, Kilbourne J, Yaron J, Lowe KM, Daggett-Vondras J, Fonseca D, Boyd R, Wakefield D, Clapp W, Lim E, Chen H, Lucas A (2022). Virus-derived Chemokine Modulating Protein Pre-treatment Blocks Chemokine-Glycosaminoglycan Interactions and Significantly Reduces Transplant Immune Damage. Pathogens. 11(5), 588.
• Varkoly K, Tan S, Beladi R, Fonseca D, Zanetti IR, Kraberger S, Shah C, Yaron JR, Zhang L, Juby L, Fath AR, Ambadapadi S, House M, Maranian P, Pepine C, Varsani A, Moreb J, Schutlz-Cherry S, Lucas AR (2022). RNA Virus Gene Signatures Detected in Patients with Cardiomyopathy after Chemotherapy. Frontiers in Cardiovascular Medicine. 9, 821162

2021

• Ju B, Guo O, Benissan-Messan DZ, Shawver MH, Chen P, Geng B, Wei S, Yaron JR, Lucas AR, Hua Z (2021). Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis. Frontiers in Cardiovascular Medicine. 8, 649124
• Yaron JR, Zhang L, Guo Q, Haydel SE, Lucas AR (2021). Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms. Frontiers in Cardiovascular Medicine. 8, 648947
• Beladi RN†, Varkoly KS†, Schutz L†, Zhang L, Yaron JR, Guo Q, Burgin M, Hogue I, Tierney W, Dabrowski W, Lucas AR (2021). Serine Proteases and Chemokines in Neurotrauma; New Targets for Immune Modulating Therapeutics in Spinal Cord Injury. Current Neuropharmacology. 19(11):1835-1854. (†Equal Contributions)
• Guo Q, Yaron JR, Wallen III JW, Browder KF, Boyd R, Olson TL, Burgin M, Ulrich P, Aliskevich E, Schutz LN, Fromme P, Zhang L, Lucas A (2021). PEGylated Serp-1 Markedly Reduces Pristane-Induced Experimental Diffuse Alveolar Hemorrhage, Altering uPAR Distribution, and Macrophage Invasion. Frontiers in Cardiovascular Medicine. 8, 633212
• Khatua B, El Kurdi B, Patel K, Rood C, Noel P, Crowell M, Yaron J, Kostenko S, Guerra A, Faigel DO, Lowe M, Singh VP (2021). Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox. Science Advances. 7(5) eabd6449

2020

• Yaron JR†, Zhang L†, Guo Q, Awo EA, Burgin M, Schutz LN, Zhang N, Kilbourne J, Daggett-Vondras J, Lowe KM, Lucas AR (2020). Recombinant Myxoma virus-derived immune modulator M-T7 accelerates cutaneous wound healing and improves tissue remodeling. Pharmaceutics. 12(11), 1003. (†Equal Contributions)
• Fath AR, Aglan A, Platt J, Yaron JR, Varkoly KS, Beladi R, Gorgas D, Jean JT, Dasni P, Eldaly AS, Jupy M, Lucas AR (2020). Chronological Impact of Earthquakes on Blood Pressure: A Literature Review and Retrospective Study of Hypertension in Haiti before and after the 2010 Earthquake. Frontiers in Public Health. 8, 600157
• Kwiecien JM, Dabrowski W, Kwiecien-Delaney BJ, Kwiecien-Delaney CJ, Siwicka-Gieroba D, Yaron JR, Zhang L, Delaney KH, Lucas AR (2020). Neuroprotective effect of subdural infusion of Serp-1 in spinal cord trauma. Biomedicines. 8(10), 372.
• Kwiecien JM, Dabrowski W, Yaron JR, Zhang L, Delaney KH, Lucas AR (2020). The Role of Astrogliosis in Formation of the Syrinx in Spinal Cord Injury. Current Neuropharmacology. 19(2), 972.
• Ghosh D, Godeshala S, Nitiyanandan R, Islam MS, Yaron JR, DiCaudo D, Kilbourne J, Rege K (2020). Copper-Eluting Fibers for Enhanced Tissue Sealing and Repair. ACS Applied Materials & Interfaces. 12(25), 27951-27960
• Kwiecien JM†, Zhang L†, Yaron JR†, Schutz LN, Kwiecien-Delaney CJ, Awo EA, Burgin M, Dabrowski W, Lucas AR (2020). Local Chitosan-Serpin Injection after Spinal Cord Injury Reduces Inflammatory Damage and Improves Neurologic Function. Journal of Clinical Medicine. 9(4), 1221 (†Equal Contributions)
• Yaron JR†, Zhang L†, Guo Q, Burgin M, Schutz L, Awo E, Wise L, Krause KL, Ildefonso CJ, Kwiecien JM, Juby M, Rahman MM, Chen H, Moyer RW, Alcami A, McFadden G, Lucas AR (2020). Deriving Immune Modulating Drugs from Viruses – A New Class of Biologics. Journal of Clinical Medicine. 9(4), 972 (†Equal Contributions)
• Kwiecien JM, Dabrowski W, Dabrowska-Bouta B, Sulkowski G, Oakden W, Kwiecien-Delaney CJ, Yaron JR, Zhang L, Schutz L, Marzec-Kotarska B, Stanisz GJ, Karis JP, Struzynska L, Lucas AR (2020). Prolonged inflammation leads to ongoing damage after spinal cord injury. PLoS ONE. 15(3), e0226584
• Yaron JR†, Ambadapadi S†, Zhang L, Chavan RN, Tibbetts SA, Keinan S, Varsani A, Maldonado J, Tafoya AM, Bullard WL, Kilbourne J, Stern-Harbutte A, Krajmalnik-Brown R, Munk BH, Koppang EO, Lim ES, Lucas AR (2020). Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection. Scientific Reports. 10(1), 1-13 (†Equal Contributions)
• Khatua B, Yaron JR, El-Kurdi B, Kostenko S, Papachristou GI, Singh VP (2020). Ringer’s lactate prevents early organ failure by providing extracellular calcium. Journal of Clinical Medicine. 9(1), 263

2019

• Zhang L†, Yaron JR†, Tafoya AM, Wallace SE, Kilbourne J, Haydel S, Rege K, McFadden G, Lucas AR (2019). A virus-derived immune modulating SERPIN accelerates wound closure with improved collagen remodeling. Journal of Clinical Medicine. 8(1626), 1-17 (†Equal Contributions)
  • Selected as issue cover
• Yaron JR†, Chen H†, Ambadapadi S†, Zhang L, Tafoya AM, Munk BH, Wakefield D, Fuentes J, Marques BJ, Harripersaud K, Bartee MY, Davids J, Zheng D, Rand K, Dixon L, Moyer R, Clapp W, Lucas AR (2019). Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice. Journal of Inflammation. 16(1), 12 (†Equal Contributions)
• Yaron JR†, Kwiecien JM†, Zhang L†, Ambadapadi S, Wakefield DN, Clapp WL, Dabrowski W, Burgin M, Munk BH, McFadden G, Chen H, Lucas AR (2019). Modifying the Organ Matrix Pre-Engraftment; A New Transplant Paradigm? Trends in Molecular Medicine. 25(7), 626-639 (†Equal Contributions)
• Kwiecien JM, Dabrowski W, Marzec-Kotarska B, Kwiecien-Delaney CJ, Yaron JR, Zhang L, Schutz L, Lucas AR (2019). Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model. Folia Neuropathologica. 57(1), 41-50

2018

• Chen H, Bartee M, Yaron J, Liu L, Zhang L, Zheng D, Hogue I, Bullard W, Tibbetts S, Lucas A (2018). Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR−/−) That Is Blocked by Interleukin-10. Viruses. 10(10), 518
• Kostenko S, Heu CC, Yaron JR, Singh G, Oliveira CD, Muller WJ, Singh VP (2018). c-Src Regulates Cargo Transit via the Golgi in Pancreatic Acinar Cells. Scientific Reports. 8(1), 11903
• Chen H, Ambadapadi S, Wakefield D, Bartee MY, Yaron JR, Zhang L, Archer-Hartmann SA, Azadi P, Burgin M, Borges C, Zheng D, Ergle K, Muppala V, Morshed S, Rand K, Clapp W, Proudfoot A, Lucas A (2018). Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection. Scientific Reports. 8(1), 13433
• Mahon BP, Ambadapadi S, Yaron JR, Lomelino CL, Pinard MA, Keinan S, Kurnikov I, Macaulay C, Zhang L, Reeves W, McFadden G, Tibbetts S, McKenna R, Lucas AR (2018). Crystal Structure of Serp-1, a Myxomavirus-derived Immune Modulating Serpin; Structural Design of Serpin Reactive Center Loop (RCL) Peptides with Improved Therapeutic Function. Biochemistry. 57(7), 1096-1107

2017

• Al-Ani M†, Ambadapadi S†, Yaron JR†, Zheng D, Fortunel A, Doroton-Guevara M, Liu L, Morshed S, Fricker J, Miles W, McKillop M, Lucas A (2017). Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation. Cardiovascular and Hematologic Disorders: Drug Targets. 17(3), 195-204 (†Equal Contributions)
• Lucas A, Ambadapadi S, Mahon B, Viswanathan K, Chen H, Liu L, Dai E, Munuswami-Ramanujam G, Kwiecien JM, Yaron JR, Narute PS, McKenna R, Keenan S, Brantly M, McFadden G (2017). The Serpintine Solution. Journal of Clinical and Experimental Cardiology. 8(1), e150

2016

• Yaron JR, Rao MY, Gangaraju S, Zhang L, Kong X, Su F, Tian Y, Glenn HL, Meldrum DR (2016). The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux. Biochemical and Biophysical Research Communications. 472(3), 545-550
• Oliveira CD, Patel K, Mishra V, Trivedi RN, Noel P, Singh A, Yaron JR, Singh VP (2016). Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis. PLoS ONE. 11(2), e0149073

2015

• Yaron JR, Gangaraju S, Rao MY, Kong X, Zhang L, Su F, Tian Y, Glenn HL, Meldrum DR (2015). K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells. Cell Death and Disease. 6(10), e1954
• Kong X, Su F, Zhang L, Yaron J, Lee F, Shi Z, Tian Y, Meldrum DR (2015). A Highly Selective Mitochondria-Targeting Fluorescent K+ Sensor. Angewandte Chemie: International Edition. 54(41), 12053-12057

2014

• Yaron JR, Ziegler CP, Tran TH, Glenn HL, Meldrum DR (2014). A convenient, optimized pipeline for isolation, fluorescence microscopy and molecular analysis of live single cells. Biological Procedures Online. 16(9)