Emily Higgins Keppler

Grad Research Assistant, Biodesign Center for Fundamental & Applied Microbiomics

PhD Student - Mentor: Heather Bean, PhD, Microbiology PhD Students

emily.higgins@asu.edu

Life Sciences Wing E (LSE) Room 317 Tempe, AZ 85287
Mail code: 6101

Campus: Tempe
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Student Information

Graduate Student
Microbiology
The College of Lib Arts & Sci

Long Bio

Emily Higgins Keppler is a Ph.D. candidate in Heather Bean's lab. Emily currently has two main research projects:

Project I: Identification of bacterial volatile compounds that inhibit fungal growth

Project II: Volatile biomarkers associated with coccidioidomycosis (Valley Fever) infections

Emily is using two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS) to identify the volatile metabolites produced by the microbial community associated with each of these projects.

Education

Ph.D. Arizona State University - Microbiology (In Progress)

Dissertation: Volatile biomarkers for a Valley fever breath test

Advisor: Heather D. Bean, PhD

B.S. Arizona State University - Microbiology (2015) Graduated Cum Lade

B.A. Arizona State University - Anthropology (2005)

Curriculum Vitae (0 bytes)

Images

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Video

Research Website URL

https://www.the-bean-lab.com/

Google Scholar URL

https://scholar.google.com/citations?user=g_OYspMAAAAJ&hl=en

Publications

Emily A. Higgins Keppler, Marley C. Cabellero Van Dyke, Heather L. Mead, Douglas F. Lake, D. Mitchell Magee, Bridget M. Barker, and Heather D. Bean. (Submitted - mBio) Volatile metabolites in lavage fluid are correlated to Valley fever disease severity in murine model lung infections. BioRxiv: https://www.biorxiv.org/content/10.1101/2022.10.02.510537v1

Trenton J. Davis*, Tarek R. Firzli*, Emily A. Higgins Keppler*, Matthew Richardson, and Heather D. Bean. (2022) Addressing missing data in GCxGC metabolomics: Identifying missingness type and evaluating the impact of imputation methods on experimental replication. Analytical Chemistry, 94, 10912-10920. https://doi.org/10.1021/acs.analchem.1c04093

Emily A. Higgins Keppler, Heather L. Mead, Bridget M. Barker, and Heather D. Bean. (2021) Life cycle dominates the volatilome character of the dimorphic fungus Coccidioides spp. mSphere 6:e00040-21. https://doi.org/10.1128/mSphere.00040-21

Ghazal Ebadzadsahrai, Emily A. Higgins Keppler, Scott D. Soby, Heather D. Bean. (2020) Inhibition of fungal growth and induction of a novel volatilome in response to Chromobacterium vaccinii volatile organic compounds. Frontiers in Microbiology 11:1035, pp 1-17. https://doi.org/10.3389/fmicb.2020.01035

H.L. Mead, C.C. Roe, E.A. Higgins Keppler, M.C.C. Van Dyke, K.L. Laux, A.L. Funke, K.J. Miller, H.D. Bean, J.W. Sahl, B.M. Barker. (2020) Defining critical genes during spherule remodeling and endospore development in the fungal pathogen, Coccidioides posadasii. Frontiers in Genetics 11:483, pp 1-18. https://doi.org/10.3389/fgene.2020.00483

Emily A. Higgins Keppler, Carrie L. Jenkins, Trenton J. Davis, Heather D. Bean. (2018) Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics. Trends in Analytical Chemistry 109, pp 275 286. https://doi.org/10.1016/j.trac.2018.10.015