Emily Higgins Keppler

Assistant Research Scientist,

Fundamental & Applied Microbiomics Researchers

Other ASU affiliations

Biodesign Center for Fundamental & Applied Microbiomics

Emily.Higgins@asu.edu

Life Sciences Wing E (LSE) Room 317 Tempe, AZ 85287
Mail code: 6101

Campus: Tempe
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Long Bio

Emily Higgins Keppler is an Assistant Research Scientist in Heather Bean's lab.

Emily is using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOFMS) to investigate volatile biomarkers for diagnosing disease.

Education

Ph.D. Arizona State University - Microbiology (2023)

Dissertation: Volatile biomarkers for a Valley fever breath test

Advisor: Heather D. Bean, PhD

B.S. Arizona State University - Microbiology (2015) Graduated Cum Lade

B.A. Arizona State University - Anthropology (2005)

Curriculum Vitae

Images

IABR_twitter_GIF.gif

Video

Research Website URL

https://www.the-bean-lab.com/

Google Scholar URL

https://scholar.google.com/citations?user=g_OYspMAAAAJ&hl=en

ORCID Profile ID

https://orcid.org/0000-0001-9197-1555

Research Interests

Volatile biomarkers for diagnosing disease

Valley fever

Coccidioidomycosis

Research Group

Bean Lab

Publications

Jenna Diefenderfer, Heather D. Bean, Emily A. Higgins Keppler. (2024) New breath diagnostics for fungal disease. Current Clinical Microbiology Reports. https://doi.org/10.1007/s40588-024-00216-x

Emily A. Higgins Keppler, Marley C. Cabellero Van Dyke, Heather L. Mead, Douglas F. Lake, D. Mitchell Magee, Bridget M. Barker, and Heather D. Bean. (2023) Volatile metabolites in lavage fluid are correlated with cytokine production in a Valley fever murine model. Journal of Fungi, 9(1):115. https://doi.org/10.3390/jof9010115 

Trenton J. Davis*, Tarek R. Firzli*, Emily A. Higgins Keppler*, Matthew Richardson, and Heather D. Bean. (2022) Addressing missing data in GCxGC metabolomics: Identifying missingness type and evaluating the impact of imputation methods on experimental replication. Analytical Chemistry, 94, 10912-10920. https://doi.org/10.1021/acs.analchem.1c04093

Emily A. Higgins Keppler, Heather L. Mead, Bridget M. Barker, and Heather D. Bean. (2021) Life cycle dominates the volatilome character of the dimorphic fungus Coccidioides spp. mSphere 6:e00040-21. https://doi.org/10.1128/mSphere.00040-21

Ghazal Ebadzadsahrai, Emily A. Higgins Keppler, Scott D. Soby, Heather D. Bean. (2020) Inhibition of fungal growth and induction of a novel volatilome in response to Chromobacterium vaccinii volatile organic compounds. Frontiers in Microbiology 11:1035, pp 1-17. https://doi.org/10.3389/fmicb.2020.01035

H.L. Mead, C.C. Roe, E.A. Higgins Keppler, M.C.C. Van Dyke, K.L. Laux, A.L. Funke, K.J. Miller, H.D. Bean, J.W. Sahl, B.M. Barker. (2020) Defining critical genes during spherule remodeling and endospore development in the fungal pathogen, Coccidioides posadasii. Frontiers in Genetics 11:483, pp 1-18. https://doi.org/10.3389/fgene.2020.00483

Emily A. Higgins Keppler, Carrie L. Jenkins, Trenton J. Davis, Heather D. Bean. (2018) Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics. Trends in Analytical Chemistry 109, pp 275 286. https://doi.org/10.1016/j.trac.2018.10.015

Honors / Awards

2023 Fusion – Aristotle Poster Award for Most Transdisciplinary Approach

2022 Journal of Fungi Editor's Choice Article: https://doi.org/10.3390/jof9010115

2022 ASU Graduate College Completion Fellowship

2022 ASU Graduate College University Grant

2022 ASM AZ/S. NV Branch Meeting – 1st Place, Best Poster Presentation

2022 ASU GPSA Outstanding Researcher Award

2022 LoBrutto Family Fund Fellowship

2022 The College’s Graduate Excellence Award

2022 Multidimensional Chromatography Workshop – Multidimensional GC Poster Prize

2022 Harry Lowell Swift Advancing Health Scholarship

2021 GRSP Lightning Talk – Life & Physical Sciences Best Presenter Award