The Wadhwa lab employs a combination of biophysical experiments and theoretical modeling to investigate how physical forces influence the behavior of living matter at scales ranging from single molecules to whole cells. Current projects in the lab include how bacteria generate, sense, and respond to physical forces and how these forces are transduced into biochemical signals to modulate behavior. Our research is supported by grants from the National Institutes of Health, Arizona Biomedical Research Centre, and the Biological Integration Institute for Mechanisms of Cellular Evolution.
The Wadhwa lab is recruiting postdocs and graduate students. Interested candidates should visit our website and contact Navish at Navish.Wadhwa@asu.edu.
Physics of Biological Systems; Soft Matter Physics;
Publications
Recent Publications:
Wadhwa, N., & Berg, H. C. (2022). Bacterial motility: machinery and mechanisms. Nature reviews microbiology, 20(3), 161-173.
Ergin, F. G., Günaydınoğlu, E., Kurtuluş, D. F., & Wadhwa, N. (2023). Estimating the pressure force around swimming plankton using micro particle image velocimetry. Fluid Dynamics Research, 55(6), 065505.
Hu, H., Popp, P. F., Santiveri, M., Roa-Eguiara, A., Yan, Y., Martin, F. J., ... & Taylor, N. M. (2023). Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit. Nature communications, 14(1), 4411.
Wadhwa, N., Sassi, A., Berg, H. C., & Tu, Y. (2022). A multi-state dynamic process confers mechano-adaptation to a biological nanomachine. Nature communications, 13(1), 5327.
Wadhwa, N., Tu, Y., & Berg, H. C. (2021). Mechanosensitive remodeling of the bacterial flagellar motor is independent of direction of rotation. Proceedings of the National Academy of Sciences, 118(15), e2024608118.
Santiveri, M., Roa-Eguiara, A., Kühne, C., Wadhwa, N., Hu, H., Berg, H. C., ... & Taylor, N. M. (2020). Structure and function of stator units of the bacterial flagellar motor. Cell, 183(1), 244-257.
Wadhwa, N., Phillips, R., & Berg, H. C. (2019). Torque-dependent remodeling of the bacterial flagellar motor. Proceedings of the National Academy of Sciences, 116(24), 11764-11769.