Vel Murugan

Peer Reviewed Articles:

1. Frutos AM, Price AM, Harker E, Reeves EL, Ahmad HM, Murugan V, et al. Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States. MMWR Morb Mortal Wkly Rep. 2024;73(8):168-74.
2. Song L, Rauf F, Hou CW, Qiu J, Murugan V, Chung Y, Lai H, Adam D, Magee DM, Trivino Soto G, Peterson M, Anderson KS, Rice SG, Readhead B, Park JG, LaBaer J. Quantitative assessment of multiple pathogen exposure and immune dynamics at scale. Microbiol Spectr. 2023:e0239923. Epub 20231208. doi: 10.1128/spectrum.02399-23. PubMed PMID: 38063388.
3. Holland, L.A., Holland, S.C., Smith, M.F., Leonard, V.R., Murugan, V., Nordstrom, L., Mulrow, M., Salgado, R., White, M., and Lim, E.S. (2023). Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA. Emerg Infect Dis 29. 10.3201/eid2911.230836.
4. Sasser, J., Li, C.B., Doane, L.D., Krasnow, A., Murugan, V., Magee, D.M., and LaBaer, J. (2023). Associations between COVID-19 sleep patterns, depressive symptoms, loneliness, and academic engagement: a latent profile analysis. J Am Coll Health, 1-5. 10.1080/07448481.2023.2239361.
5. Lee, R.E., Todd, M., Oh, H., Han, S., Santana, M., Aguilar-Troncoso, J., Bruening, M., Kramer, J.L., Leon, T., Murugan, V., et al. (2023). Acceptability and Feasibility of Saliva-delivered PCR Coronavirus 2019 Tests for Young Children. Pediatrics 152. 10.1542/peds.2022-060352D.
6. Hou, C.W., Williams, S., Taylor, K., Boyle, V., Bobbett, B., Kouvetakis, J., Nguyen, K., McDonald, A., Harris, V., Nussle, B., et al. (2023). Serological survey to estimate SARS-CoV-2 infection and antibody seroprevalence at a large public university: A cross-sectional study. BMJ Open 13, e072627. 10.1136/bmjopen-2023-072627.
7. Goldman, J.L., Kalu, I.C., Schuster, J.E., Erickson, T., Mast, D.K., Zimmerman, K., Benjamin, D.K., Kalb, L.G., Gurnett, C., Newland, J.G., et al. (2023). Building School-Academic Partnerships to Implement COVID-19 Testing in Underserved Populations. Pediatrics 152. 10.1542/peds.2022-060352C.
8. Troup, C., Mukhopadhyay, D., Chakrabarty, T., Madan, A., Dwarakanath, S., Murugan, V., and Satyanarayana, S. (2023). Accurate and Rapid Antigen Assay for COVID-19 Diagnostics Using Saliva. Archives of Clinical and Biomedical Research 07, 133-146. 10.26502/acbr.50170326.
9. Smith, M.F., Holland, S.C., Lee, M.B., Hu, J.C., Pham, N.C., Sullins, R.A., Holland, L.A., Mu, T., Thomas, A.W., Fitch, R., Driver EM, Halden RU, Villegas-Gold M, Sanders S, Krauss JL, Nordstrom L, Mulrow M, White M, Murugan V, Lim ES (2023). Baseline Sequencing Surveillance of Public Clinical Testing, Hospitals, and Community Wastewater Reveals Rapid Emergence of SARS-CoV-2 Omicron Variant of Concern in Arizona, USA. mBio, e0310122. 10.1128/mbio.03101-22.
10. Qiu, J., Engelbrektson, A., Song, L., Park, J., Murugan, V., Williams, S., Chung, Y., Pompa-Mera, E.N., Sandoval-Ramirez, J.L., Mata-Marin, J.A., et al. (2023). Comparative Analysis of Antimicrobial Antibodies between Mild and Severe COVID-19. Microbiol Spectr, e0469022. 10.1128/spectrum.04690-22.
11. Lal D, Song L, Brar T, Cope EK, Keim P, Williams S, Chung Y, Murugan V, LaBaer J, Magee DM. (2022) Antibody responses to the host microbiome in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2022. Epub 20221211. doi: 10.1002/alr.23107. PubMed PMID: 36504343.
12. Shome, M., Gao, W., Engelbrektson, A., Song, L., Williams, S., Murugan, V., Park, J.G., Chung, Y., LaBaer, J., and Qiu, J. (2022a). Comparative microbiomics analysis of anti-microbial antibody response between lung cancer patients and control subjects with benign pulmonary nodules. Cancer Epidemiol Biomarkers Prev. 10.1158/1055-9965.Epi-22-0384.
13. Shome, M., Song, L., Williams, S., Chung, Y., Murugan, V., Park, J.G., Faubion, W., Pasha, S.F., Leighton, J.A., LaBaer, J., and Qiu, J. (2022b). Serological profiling of Crohn's disease and ulcerative colitis patients reveals anti-microbial antibody signatures. World J Gastroenterol 28, 4089-4101. 10.3748/wjg.v28.i30.4089.
14. Holland, S.C., Bains, A., Holland, L.A., Smith, M.F., Sullins, R.A., Mellor, N.J., Thomas, A.W., Johnson, N., Murugan, V., and Lim, E.S. (2022). SARS-CoV-2 Delta Variant N Gene Mutations Reduce Sensitivity to the TaqPath COVID-19 Multiplex Molecular Diagnostic Assay. Viruses 14. 10.3390/v14061316.
15. Karger AB, Brien JD, Christen JM, Dhakal S, Kemp TJ, Klein SL, Pinto LA, Premkumar L, Roback JD, Binder RA, Boehme KW, Boppana S, Cordon-Cardo C, Crawford JM, Daiss JL, Dupuis AP, 2nd, Espino AM, Firpo-Betancourt A, Forconi C, Forrest JC, Girardin RC, Granger DA, Granger SW, Haddad NS, Heaney CD, Hunt DT, Kennedy JL, King CL, Krammer F, Kruczynski K, LaBaer J, Lee FE, Lee WT, Liu SL, Lozanski G, Lucas T, Mendu DR, Moormann AM, Murugan V, Okoye NC, Pantoja P, Payne AF, Park J, Pinninti S, Pinto AK, Pisanic N, Qiu J, Sariol CA, Simon V, Song L, Steffen TL, Stone ET, Styer LM, Suthar MS, Thomas SN, Thyagarajan B, Wajnberg A, Yates JL, Sobhani K. The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization. mSphere. 2022;7(4):e0019322. Epub 20220615. doi: 10.1128/msphere.00193-22. PubMed PMID: 35703544; PMCID: PMC9429934.
16. Hoffmeyer, M.R., Gillis, K., Park, J.G., Murugan, V., and LaBaer, J. (2021). Making the Case for Absorbed Radiation Response Biodosimetry - Utility of a High-Throughput Biodosimetry System. Radiat Res 196, 535-546.
17. Pannala, R., Gupta, S., Tinkasimile, A.K., Vorachitti, M., Faigel, D.O., Grys, T.E., LaBaer, J., and Murugan, V. (2020). 95 QUANTITATIVE QPCR-BASED BIOBURDEN TEST FOR THE DETECTION OF CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE): NOVEL TEST FOR SURVEILLANCE AND RISK-STRATIFICATION. Gastrointestinal Endoscopy 91, AB12-AB13
18. Skidmore, P.T., Kaelin, E.A., Holland, L.A., Maqsood, R., Wu, L.I., Mellor, N.J., Blain, J.M., Harris, V., LaBaer, J., Murugan, V., and Lim, ES. (2021). Genomic Sequencing of SARS-CoV-2 E484K Variant B.1.243.1, Arizona, USA. Emerg Infect Dis 27, 2718-2720.
19. Sá JM, Kaslow SR, Krause MA, Melendez-Muniz VA, Salzman RE, Kite WA, Zhang M, Moraes Barros RR, Mu J, Han PK, Mershon JP, Figan CE, Caleon RL, Rahman RS, Gibson TJ, Amaratunga C, Nishiguchi EP, Breglio KF, Engels TM, Velmurugan S, Ricklefs S, Straimer J, Gnädig NF, Deng B, Liu A, Diouf A, Miura K, Tullo GS, Eastman RT, Chakravarty S, James ER, Udenze K, Li S, Sturdevant DE, Gwadz RW, Porcella SF, Long CA, Fidock DA, Thomas ML, Fay MP, Sim BKL, Hoffman SL, Adams JH, Fairhurst RM, Su XZ, Wellems TE. Proc. Natl. Acad. Sci. (2018) 115(49); 12513-12518.
20. Naetar, N*., Velmurugan, S*., Litovchick, L., Goguen, KL., Sablina, A, Bowman-Colin, B., Sicinski, P., Hahn, WC., DeCaprio, J., and Livingston, DL PP2A-Mediated Regulation of Ras Signaling in G2 Is Essential for Stable Quiescence and Normal G1 Length. Mol. Cell (2014) 54; 1-14. *Authors contributed equally to this work.
21. Seder, R. A., L. J. Chang, M. E. Enama, K. L. Zephir, U. N. Sarwar, I. J. Gordon, L. A. Holman, E. R. James, P. F. Billingsley, A. Gunasekera, A. Richman, S. Chakravarty, A. Manoj, S. Velmurugan, M. Li, A. J. Ruben, T. Li, A. G. Eappen, R. E. Stafford, S. H. Plummer, C. S. Hendel, L. Novik, P. J. Costner, F. H. Mendoza, J. G. Saunders, M. C. Nason, J. H. Richardson, J. Murphy, S. A. Davidson, T. L. Richie, M. Sedegah, A. Sutamihardja, G. A. Fahle, K. E. Lyke, M. B. Laurens, M. Roederer, K. Tewari, J. E. Epstein, B. K. Sim, J. E. Ledgerwood, B. S. Graham, S. L. Hoffman, and V. R. C. Study Team the. "Protection against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine." Science,  (2013) 341(6152):1359-65.
22. March, S., S. Ng, S. Velmurugan, A. Galstian, J. Shan, D. J. Logan, A. E. Carpenter, D. Thomas, B. K. Sim, M. M. Mota, S. L. Hoffman, and S. N. Bhatia. "A Microscale Human Liver Platform That Supports the Hepatic Stages of Plasmodium Falciparum and Vivax." Cell Host Microbe 14, no. 1 (2013): 104-15.
23. Roestenberg, M., E. M. Bijker, B. K. Sim, P. F. Billingsley, E. R. James, G. J. Bastiaens, A. C. Teirlinck, A. Scholzen, K. Teelen, T. Arens, A. J. van der Ven, A. Gunasekera, S. Chakravarty, S. Velmurugan, C. C. Hermsen, R. W. Sauerwein, and S. L. Hoffman. "Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium Falciparum Sporozoites." Am J Trop Med Hyg 88, no. 1 (2013): 5-13.
24. Fine, D.A., Rosen, R., Padi, M., Korkhin. A., James, R.L., Adelmant, G., Yoon, R., Guo, L., Berrios, C., Zhang, Y., Calderwood, M.A., Velmurugan, S., Cheng, J., Marto, J.A., Hill, D.E., Cusick, M.E., Vidal, M., Florens, L., Washburn, M.P., Litovchick, L., and DeCaprio. J.A. (2012) Identification of FAM111A as an SV40 host range restriction factor. PLoS Pathog 8(10): e1002949. doi:10.1371/ journal.ppat.1002949
25. Hoffman, S.A., Aravind, L and Velmurugan, S. (2012). Female Anopheles gambiae antennae: increased transcript accumulation of the mosquito-specific odorant-binding-protein OBP2. Parasites and Vectors 5:27 (doi:10.1186/1756-3305-5-27)
26. Epstein, J.E., Tewari, K., Lyke, K.E., Sim, B.K.L., Billingsley, P.F., Laurens, M.B., Gunasekera, A., Chakravarty, S., James, E.R., Sedegah, M., Richman, A., Velmurugan, S., Reyes, S., Li, M., Tucker, K., Ahumada, A., Ruben, A.J., Li, T., Stafford, R., Eappen, A.G., Tamminga, C., Bennett, J.W., Ockenhouse, C.F., Murphy, J.R., Komisar, J., Thomas, N., Loyevsky, M., Birkett, A., Plowe, C.V., Loucq, C., Edelman, R., Richie, T.L., Seder, R.A., Hoffman, S.L. (2011) Live Attenuated Malaria Vaccine Designed to Protect through Hepatic CD8+ T Cell Immunity. Science (2011) 334(6055):475-80 (DOI: 10.1126/science.1211548)
27. Chattopadhyay,R., Velmurugan, S., Chakiath, C., Andrews Donkor, L., Milhous, W., Barnwell, J.W., Collins, W.E.,  and Hoffman, S.L (2010) Establishment of an In Vitro Assay for Assessing the Effects of Drugs on the Liver Stages of Plasmodium vivax malaria. PloSONE 5: e14275
28. Tewari, K., Flynn, B.J., Boscardin, S.B, Kastenmueller, K., Salazar, A.M., Anderson, C.A., Velmurugan, S., Ahumada, A., Keler, T., Hoffman, S.L., Nussenzweig, M.C., Steinman, R.M., and Seder, R.A. (2010) Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non-human primates. Vaccine 45: 7256-7266
29. Litovchick, L., Sadasivam, S., Florens, L., Zhu, X., Swanson, S.K., Velmurugan, S., Washburn, M.K., Liu, X.S. and DeCaprio J.A. (2007) Evolutionally conserved multi-subunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol. Cell. 26: 539-551.
30. Silver, D.P., Dimitrov, S., Feunteun, J., Gelman, R., Mar, J., Drapkin, R., Lu, D., Shestakova, E., Velmurugan, S., DeNunzio, N., Dragomir, S., Liu, X., Rottenberg , S., Jonkers, J., Ganesan, S and Livingston, D.M. (2007) Further Evidence for BRCA1 Communication with the Inactive X Chromosome. Cell 128: 991-1002
31. Dobson, M.J., Pickett, A.J., Velmurugan, S., Pinder, J.B., Barrett, L.A., Jayaram, M and Chew, J.S. (2005) The 2-micron plasmid causes cell death in Saccharomyces cerevisiae with a mutation in Ulp1 protease. Mol. Cell. Biol. 25: 4299-4310.
32. Mehta, S., Yang, X., Jayaram, M., and Velmurugan. S. (2005) A novel role for the mitotic spindle during DNA segregation in yeast: promoting 2-micron plasmid-cohesin association. Mol. Cell. Biol. 25: 4283-4298.
33. Yang, X., Mehta, S., Uzri, D., Jayaram, M., and Velmurugan, S. (2004) Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the yeast plasmid and cause its missegregation. Mol. Cell. Biol. 24: 5290-5303.
34. Mehta, S., Yang, X., Chan, C. S. M., Dobson, M. M., Jayaram, M., and Velmurugan. S. (2002). Coupling between 2-micron plasmid partitioning and chromosome segregation in yeast: the plasmid stability system purloins the yeast cohesin complex? J. Cell Biol. 158, 625-637.
35. Kang J. S., Cheeseman, I. M., Kallstrom, G., Velmurugan, S., Barnes, G., and Chan, C. S. (2001). Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation. J. Cell Biol. 155, 763-774.
36. Lisby, M., Olesen, J. R., Skouboe, C., Krogh, B. O., Straub, T., Boege, F., Velmurugan, S., Martensen, P. M., Andersen, A. H., Jayaram, M., and Knudsen, B. R. (2001). Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation. J. Biol. Chem. 276, 20220-20227.
37. Velmurugan, S., Yang, X. M., Chan, C. S., Dobson, M., and Jayaram, M. (2000). Partitioning of the 2-micron circle plasmid of Saccharomyces cerevisiae. Functional coordination with chromosome segregation and plasmid-encoded rep protein distribution. J. Cell Biol. 149, 553-566.
38. Velmurugan, S., Ahn, Y. T., Yang, X. M., Wu, X. L., and Jayaram, M. (1998). The 2-micron plasmid stability system: analyses of the interactions among plasmid- and host-encoded components. Mol. Cell Biol. 18, 7466-7477.
39. Mehta, S., Velmurugan, S., and Lobo, Z. (1998). Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast. FEBS Lett. 440, 430-433.
40. Mehta, S. V., Patil, V. B., Velmurugan, S., Lobo, Z., and Maitra, P. K. (1998). Std1, a gene involved in glucose transport in Schizosaccharomyces pombe. J. Bacteriol. 180, 674-679.
41. Velmurugan, S., Lobo, Z., and Maitra, P. K. (1997). Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145, 587-594.
42. Ahn, Y. T., Wu, X. L., Biswal, S., Velmurugan, S., Volkert, F. C., and Jayaram, M. (1997). The 2 µm-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus. J. Bacteriol. 179, 7497-7506.
43. Gunasekaran, P., Mukundan, G., Kannan, T. R., Velmurugan, S., Ait-Abdelkader, N., and Baratti, J. (1995). The SacB and SacC genes encoding levansucrase and sucrase form a gene cluster in Zymomonas mobilis. Biotechnol. letters 17, 635-642

Published in preprint archives.

42. Ridha I, Xu C, Chung Y, Park JG, LaBaer J, Murugan V. Multiplexed Methylated DNA Immunoprecipitation Sequencing (Mx-MeDIP-Seq) to Study DNA Methylation Using Low Amounts of DNA. (2023) bioRxiv. 2023:2023.01.09.523163. doi: 10.1101/2023.01.09.523163.
43. Ching-Wen, H., Stacy, W., Guillermo, T.-S., Veronica, B., David, R., Selina, V., Mitch, M., Yunro, C., Joshua, L., and Vel, M. (2023). Estimating seroprevalence of SARS-CoV-2 infection after a highly contagious Omicron outbreak: A cross sectional study in a university setting. medRxiv, 2023.2008.2029.23293775. 10.1101/2023.08.29.23293775.

Review Articles

1. Jayaram, M., Mehta, S., Uzri, D., Voziyanov, Y., and Velmurugan, S. (2004). Site-specific Recombination and Partitioning Systems in the Stable High Copy Propagation of the 2 Micron Yeast Plasmid. In Prog. Nucleic Acid Res. Mol. Biol. 77: 127-172
2. Jayaram, M., Mehta, S., Uzri, D., and S. Velmurugan. (2004) Segregation of the Yeast Plasmid: Similarities and Contrasts with Bacterial Plasmid Partitioning. Plasmid. 51: 162-178.
3. Velmurugan, S., Mehta, S., and Jayaram, M. (2003). Selfishness in moderation: evolutionary success of the yeast plasmid. Curr. Topics Dev. Biol. 56, 1-24.
4. Jayaram, M., Mehta, S., Uzri, D., and S. Velmurugan. (2003) Stable propagation of 'selfish' genetic elements. J. Biosci. 5, 623-636.
5. Mehta, S., Jayaram, M and Velmurugan, S. (2003). Yeast plasmids: models for the evolutionary persistence of selfish extrachromosomal elements. In Recent Research Developments in Molecular and Cellular Biology 4, 249-271.

Book Chapters

1. Jayaram, M., Yang, X., Mehta, S., Voziyanov, Y., and Velmurugan, S. (2004). The 2-micron plasmid of Saccharomyces cerevisiae. In Plasmid Biology. Eds Funnell, B. E., and Philips, G. J., ASM Press, Washington DC.

Published in preprint archives.

1. Ridha I, Xu C, Chung Y, Park JG, LaBaer J, Murugan V. Multiplexed Methylated DNA Immunoprecipitation Sequencing (Mx-MeDIP-Seq) to Study DNA Methylation Using Low Amounts of DNA. (2023) bioRxiv. 2023:2023.01.09.523163. doi: 10.1101/2023.01.09.523163.
2. Ching-Wen, H., Stacy, W., Guillermo, T.-S., Veronica, B., David, R., Selina, V., Mitch, M., Yunro, C., Joshua, L., and Vel, M. (2023). Estimating seroprevalence of SARS-CoV-2 infection after a highly contagious Omicron outbreak: A cross sectional study in a university setting. medRxiv, 2023.2008.2029.23293775. 10.1101/2023.08.29.23293775.

Conference Presentations since Joining ASU

1. Oct 16 - 19, 2016 Radiation Research Society Meeting:

Development of an acute exposure human biodosimeter using human and nonhuman primate test models

2. Jan 14-18, 2019: Protein Science Week; Alternative Expression and Products

High-Throughput Cloning for Biomarker Discovery and Functional Genomics

3. Sept 24-16, 2019: New Perspectives, Technology Frontiers & Investment Trends in Synthetic Biology. Session: Dawn of smart biomanufacturing: innovative tools and applications in synthetic biology

Synthetic Biology in Rapid Biomarker Discovery and Development

4. July 25-29 Plant Biology 2020:

NAPPA-Desalting Paper Spray Mass Spectrometry pipeline as a tool for functional characterization of glycosyltransferases

5. Jan 23-24, 2020, Higher-Throughput Protein Production & Characterization:

High-Throughput Cloning and IVTT Expression for Biomarker Discovery and Functional Genomics

6. Oct 01-06; 2021 RRS annual conference:

Low-Cost Point-Of-Care Biodosimeter to Predict Radiation Exposure and Bone Marrow Injuries

7. Oct 01-06; 2021 RRS annual conference:

Discovery and Development of Gene Expression Based Human Biodosimeter

8. Jan 11-15; 2023 27th Annual conference Society for social work and research

A culturally grounder intervention with vulnerable and underserved communities of the southwest U.S to reduce COVID-19 related health disparities.

9. Feb 28, 2023. Pan Community workshop.

Implementing diagnostic testing laboratory during pandemic.

10. Mar 23-25, 2023: 2023 Biennial Meeting Society for research in child development:

Student Sleep Patterns During the COVID-19 Pandemic: Links with Depressive Symptoms, Loneliness, and Academic Engagement. In "Sleep During the COVID-19 Pandemic: Evidence Among Youth, Adolescents, and Parents" Sasser, J., Li, C., Doane, L. D., Krasnow, A. D., Murugan, V., Magee, D. M., & LaBaer J. (2023, March). (Chairs: Sasser, J. & Zhang, L.). Paper presented at the Biennial Meeting of the Society for Research in Child Development, Salt Lake City, UT.

11. Apr 26-29, 2023: The 44th Annual Meeting of The Society of Behavioral medicine:

Acceptability and Feasibility of Parent Coaching to Complete Saliva-Delivered PCR COVID-2019 Tests for Hispanic Preschoolers. Lee, R.E., Todd, M., Oh, H., Han, S., Santana, M., Aguilar-Troncoso, J., Bruening, M., Kramer, J.L., Leon, T., Murugan, V., Valdez, H., and Villegas-Gold, M.

12. May 30-June 02, 2023: The 66th International Conference on Electron, Ion and Photon Beam technology and Nanofabrication:

Rapid Quantification of SARS-COV-2 Neutralizing Antibodies Using Electronic Nanoparticle Sensors. Md Ashif Ikbal, Seyedsina Mirjalili, Maziyar Kalateh Mohammadi, Yeji Choi, Mohammad Altarfa, Jose Solano, Laura A. VanBlargan, Ching-Wen Hou, Michael S. Diamond, Vel Murugan, Chao Wang.

13. Jan 16-19, 2024: PepTalk 2024. High-Throughput Bioproduction.

Genome-Scale Production of Expression Ready Clones and Distribution

14. March 20, 2024: International Conference on Applications of Artificial Intelligence In commerce and Computer Applications (AAICC-2024). Dr. Zahir Hussain College, Ilayangudi, India.

Artificial Intelligence in Healthcare