Wei Kong
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Phone: 480-727-9591
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BDB 338B TEMPE, AZ 85287-5401
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Mail code: 7401Campus: Tempe
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Wei Kong specializes in the biotechnology, vaccinology, and immunotherapy, developing microbes-based vaccines and cancer therapeutics. She is a member of the National Academy of Inventor. She also serves as faculty of Fulton Grand Challenges Scholars Program, Ira A. Fulton Schools of Engineering, and honors faculty of Barrett in the Honors College, ASU.
Dr. Kong and her team have revolutionized vaccine and therapeutic delivery strategies. They utilize genetically modifying Salmonella Typhimurium (GMS) as vehicles to deliver protective antigens encoded by genes from unrelated pathogens, DNA vaccines, and cancer therapeutics. The safety and effectiveness of these pioneering vaccines have been enhanced by including self-destructing feature, which ensures full biological containment and the successful conveyance of protective antigens, DNA vaccines, and cancer therapeutics. These innovative technologies are actively tackling global challenges by designing, constructing, and assessing live GMSs to mitigate the influence of infectious disease agents.
Additionally, Dr. Kong and her team have turned self-destructing GMS into universal tumor navigating microbe-based cancer therapeutics to combat various cancers. They also uncovered a novel mechanism of cancer to maintain and expand cancer stem cells (CSC) addition to promote cancer cell immune evasion. These findings will aid in establishing efficient therapeutic strategies for cancer treatment in the future. Recently, they have extended their research to design, construct, and evaluate gut-beneficial bacteria-based therapeutics for neurological disorders, including Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's Disease (AD).
She served as chair and reviewer of study sections, including panels with DOD Congressionally Directed Medical Research Programs Funding (MIDRP), the Military Infections Diseases Research Program of U.S. Army Medical Department (USAMD), the US Army Medical Research and Material Command (MRMC), and NIH Translational Immuno-Oncology (TIO).
Ph.D. Molecular Genetics of Bacteria, Kyushu University, Japan, 2000
Wei Kong specializes in the biotechnology, vaccinology, and immunotherapy, developing microbes-based vaccines and cancer therapeutics. Focusing on design, construction, and evaluation of vaccines to elicit protective host immune responses in agriculturally important animals and humans; design, construction and evaluation of bacteria-based cancer vaccines and therapeutics; design, construction, and evaluation of gut-beneficial bacteria-based therapeutics for neurological disorders; exploration of mechanisms of bacterial pathogenesis and host immune responses to infections and vaccines.
Center for Applied Structural Discovery
Peer reviewed research papers
Fu L, Fan J, Maity S, McFadden G, Shi Y, Kong W1. 2022. PD-L1 interacts with Frizzled 6 to activate β-catenin and form a positive feedback loop to promote cancer stem cell expansion. Oncogene. 41(8):1100-1113. PMID: 35034965. 1Corresponding authors.
Barrila J, Yang J, Franco Meléndez KP, Yang S, Buss K, Davis TJ, Aronow BJ, Bean HD, Davis RR, Forsyth RJ, Ott CM, Gangaraju S, Kang BY, Hanratty B, Nydam SD, Nauman EA, Kong W, Steel J, Nickerson CA. 2022. Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model. Front Cell Infect Microbiol. PMID: 35711662.
Jiang C, Yang D, Hua T, Hua Z, Kong W, Shi Y. 2021. A PorX/PorY and σP Feedforward Regulatory Loop Controls Gene Expression Essential for Porphyromonas gingivalis Virulence. mSphere. 6(3):e0042821. doi: 10.1128/mSphere.00428-21. PMID: 34047648
Yang D, Jiang C, Ning B, Kong W1, Shi Y1. 2021. The PorX/PorY system is a virulence factor of Porphyromonas gingivalis and mediates the activation of the type IX secretion system. J Biol Chem. 296:100574. doi: 10.1016/j.jbc.2021.100574. PMID: 33757767. 1Co-corresponding authors.
W. Kong, Xiao Wang, Emilia Fields, Blessing Okon, Mark C Jenkins, Gary Wilkins, Matthew Brovold, Tiana Golding, Amanda Gonzales, Greg Golden, Josephine Clark-Curtiss, and Roy Curtiss 3rd. 2020. Mucosal delivery of a self-destructing Salmonella-based vaccine inducing immunity against Eimeria. Avian Dis. 64(3):254-268. doi: 10.1637/aviandiseases-D-19-00159. PMID: 33112952.
Yang D, Kong Y, Sun W, Kong W1, Shi Y1. 2019. A Dopamine-Responsive Signal Transduction Controls Transcription of Salmonella enterica Serovar Typhimurium Virulence Genes. mBio. 10(2):e02772-18. doi: 10.1128/mBio.02772-18. PMID: 30992361. 1Co-corresponding author.
Hu L, Kong W, Yang D, Han Q, Guo L, Shi Y. 2019. Threonine Phosphorylation Fine-Tunes the Regulatory Activity of Histone-Like Nucleoid Structuring Protein in Salmonella Transcription. Front Microbiol. 10:1515. doi: 10.3389/fmicb.2019.01515. PMID: 31333620.
Jiang Y, Mo H, Willingham C, Wang S, Park JY, Kong W, Roland KL, Curtiss R 3rd. 2015. Protection Against Necrotic Enteritis in Broiler Chickens by Regulated Delayed Lysis Salmonella Vaccines. Avian Dis. 59(4):475-85. doi: 10.1637/11094-041715-Reg. PMID: 26629620.
Zhang X, Kong W, Wanda SY, Xin W, Alamuri P, Curtiss R 3rd. 2015. Generation of influenza virus from avian cells infected by Salmonella carrying the viral genome. PLoS One. 10(3):e0119041. doi: 10.1371/journal.pone.0119041. PMID: 25742162.
Weatherspoon-Griffin N, Yang D, Kong W, Hua Z, Shi Y. 2014. The CpxR/CpxA two-component regulatory system up-regulates the multidrug resistance cascade to facilitate Escherichia coli resistance to a model antimicrobial peptide. J Biol Chem. 289(47):32571-82. doi: 10.1074/jbc.M114.565762. PMID: 25294881.
Shi Y, Zhao G, Kong W. 2014. Genetic analysis of riboswitch-mediated transcriptional regulation responding to Mn2+ in Salmonella. J Biol Chem. 289(16):11353-11366. doi: 10.1074/jbc.M113.517516. PMID: 24596096.
1,2Kong W, Clark-Curtiss J, Curtiss R 3rd. 2013. Utilizing Salmonella for antigen delivery: the aims and benefits of bacterial delivered vaccination. Expert Rev Vaccines. 12(4):345-7. doi: 10.1586/erv.13.7. PMID: 23560914. 1Publication was highlighted by journal of Expert Review of Vaccines in “news in brief as one of the most important events and launches in the vaccines field. 2Article covered by multiple media.
Brenneman KE, Willingham C, Kong W, Curtiss R 3rd, Roland KL. 2013. Low-pH rescue of acid-sensitive Salmonella enterica Serovar Typhi Strains by a rhamnose-regulated arginine decarboxylase system. J Bacteriol. 195(13):3062-72. doi: 10.1128/JB.00104-13. PMID: 23645603.
1,2,3 Kong W, Brovold M, Koeneman BA, Clark-Curtiss J, Curtiss R 3rd. 2012. Turning self-destructing Salmonella into a universal DNA vaccine delivery platform. Proc Natl Acad Sci U S A. 109(47):19414-9. doi: 10.1073/pnas.1217554109. PMID: 23129620. 12013 Highlighted by Rees, Jenaid in Hopes for safe and cost-effective disease protection with new Salmonella bacteria vaccine technology, Expert Review of Vaccines, 12 (1), page 9. 22013 Highlighted by Riedmann, Eva M. in Self-destructing Salmonella to deliver oral DNA vaccines, Human vaccines & Immunotherapeutics, 9(2), Page 229.3Article covered by multiple media.
Zhao G, Kong W, Weatherspoon-Griffin N, Clark-Curtiss J, Shi Y. 2011. Mg2+ facilitates leader peptide translation to induce riboswitch-mediated transcription termination. EMBO J. 30(8):1485-96. doi: 10.1038/emboj.2011.66. PMID: 21399613.
Ashraf S, Kong W, Wang S, Yang J, Curtiss R 3rd. 2011. Protective cellular responses elicited by vaccination with influenza nucleoprotein delivered by a live recombinant attenuated Salmonella vaccine. Vaccine. 29(23):3990-4002. doi: 10.1016/j.vaccine.2011.03.066. PMID: 21466806.
Weatherspoon-Griffin N, Zhao G, Kong W, Kong Y, Morigen, Andrews-Polymenis H, McClelland M, Shi Y. 2011. The CpxR/CpxA two-component system up-regulates two Tat-dependent peptidoglycan amidases to confer bacterial resistance to antimicrobial peptide. J Biol Chem. 286(7):5529-39. doi: 10.1074/jbc.M110.200352. PMID: 21149452.
Zhang X, Wanda SY, Brenneman K, Kong W, Zhang X, Roland K, Curtiss R 3rd. 2011. Improving Salmonella vector with rec mutation to stabilize the DNA cargoes. BMC Microbiol. 11:31. doi: 10.1186/1471-2180-11-31. PMID: 21303535.
Ameiss K, Ashraf S, Kong W, Pekosz A, Wu WH, Milich D, Billaud JN, Curtiss R 3rd. 2010. Delivery of woodchuck hepatitis virus-like particle presented influenza M2e by recombinant attenuated Salmonella displaying a delayed lysis phenotype. Vaccine. 28(41):6704-13. doi: 10.1016/j.vaccine.2010.07.083. PMID: 20691653.
Wang S, Li Y, Scarpellini G, Kong W, Shi H, Baek CH, Gunn B, Wanda SY, Roland KL, Zhang X, Senechal-Willis P, Curtiss R 3rd. 2010. Salmonella vaccine vectors displaying delayed antigen synthesis in vivo to enhance immunogenicity. Infect Immun. 78(9):3969-80. doi: 10.1128/IAI.00444-10. PMID: 20605977.
Curtiss R 3rd, Xin W, Li Y, Kong W, Wanda SY, Gunn B, Wang S. 2010. New technologies in using recombinant attenuated Salmonella vaccine vectors. Crit Rev Immunol. 30(3):255-70. doi: 10.1615/critrevimmunol.v30.i3.30. PMID: 20370633.
Zhang X, Kong W, Ashraf S, Curtiss R 3rd. 2009. A one-plasmid system to generate influenza virus in cultured chicken cells for potential use in influenza vaccine. J Virol. 83(18):9296-303. doi: 10.1128/JVI.00781-09. PMID: 19587040.
Curtiss R 3rd, Wanda SY, Gunn BM, Zhang X, Tinge SA, Ananthnarayan V, Mo H, Wang S, Kong W. 2009. Salmonella enterica serovar typhimurium strains with regulated delayed attenuation in vivo. Infect Immun. 77(3):1071-82. doi: 10.1128/IAI.00693-08. PMID: 19103774.
Zhao G, Weatherspoon N, Kong W, Curtiss R 3rd, Shi Y. 2008. A dual-signal regulatory circuit activates transcription of a set of divergent operons in Salmonella typhimurium. Proc Natl Acad Sci U S A. 105(52):20924-9. doi: 10.1073/pnas.0807071106. PMID: 19091955.
Song H, Kong W1, Weatherspoon N, Qin G, Tyler W, Turk J, Curtiss R 3rd, Shi Y. 2008. Modulation of the regulatory activity of bacterial two-component systems by SlyA. J Biol Chem. 283(42):28158-68. doi: 10.1074/jbc.M801058200. PMID: 18678876. 1 Co-first author.
1Kong W, Wanda SY, Zhang X, Bollen W, Tinge SA, Roland KL, Curtiss R 3rd. 2008. Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment. Proc Natl Acad Sci U S A. 105(27):9361-6. doi: 10.1073/pnas.0803801105. PMID: 18607005. 1Research Highlights in News and Views, Nature Biotechnology 26, 888, doi:10.1038/nbt0808-888. 2Article highlighted in “In This Issue” PNAS. 3Article covered by multiple articles.
Kong W, Weatherspoon N, Shi Y. 2008. Molecular mechanism for establishment of signal-dependent regulation in the PhoP/PhoQ system. J Biol Chem. 283(24):16612-21. doi: 10.1074/jbc.M800547200. PMID: 18434315.
Issued Patents:
Using Tumor-Navigating Salmonella to Modulate Tumor Metabolism. Wei Kong, Lingchen Fu, Yixin Shi, Bo Ning. 2023. Issued, U.S. patent number: 11,717,542.
Tumor-delivered multi-target therapeutics for colon cancer. Wei Kong, Lingchen Fu, Yixin Shi. 2023. Issued, U.S. patent number: 11,564,954.
Tumor-navigating, self-eradicating, TRAIL-armed Salmonella for precision cancer therapy. Wei Kong. 2022. Issued, U.S. patent number: 11,519,007.
Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety. Curtiss, R. 3rd, S. Wang, S-Y. Wanda, and W. Kong. 2021. Issued, U.S. patent number: 11,180,765.
Curtiss, R. 3rd, S. Wang, S-Y. Wanda, and W. Kong. 2020. Regulated expression of antigen and/or regulated attenuation to enhance immunogenicity and/or safety (IV). Issued, U.S. patent number of 10,774,334.
Curtiss, R. 3rd, S. Wang, S-Y. Wanda, and W. Kong. 2018. Regulated expression of antigen and/or regulated attenuation to enhance immunogenicity and/or safety (III). Issued, US patent 9,885,051.
Curtiss, R. 3rd, and W. Kong. 2018. Recombinant bacterium and methods of antigen and nucleic acid delivery. Issued, US patent 9,481,888.
Curtiss, R. 3rd, and W. Kong. 2017. Recombinant bacterium to decrease tumor growth. Issued, US patent 9,598,697.
Curtiss, R. 3rd, S. Wang, S-Y. Wanda, and W. Kong. 2016. Regulated expression of antigen and/or regulated attenuation to enhance immunogenicity and/or safety (II). Issued, US patent 9,297,015 B2.
Curtiss, R. 3rd, S. Wang, S-Y. Wanda, and W. Kong. 2013. Regulated expression of antigen and/or regulated attenuation to enhance immunogenicity and/or safety (I). Issued, US patent 8,445,254 B2.
Pharmaceutical company-ASU Award. Role: PI 06/2023 - 08/2024 Title: Tumor-targeting, Self-destructing Salmonella for Cancer Therapy
Pharmaceutical company-ASU Award. Role: PI 12/2020 - 06/2023 Title: Tumor-targeting, Self-destructing Salmonella for Cancer Therapy
NIH/NCI, R21 CA249517-01A1. Role: Contact-PI 12/2020 -11/2023 Title: Cancer therapy with a combination of oncolytic bacteria and virus to enhance targeted cell killing and anti-tumor immune responses.
ASU Women & Philanthropy Award Role: PI 07/2020- - 06/2022 Title: Endue Microbes with Tumor-navigating Radar to Intelligently Hunt and Combat Breast Cancer.
NIH/NIDCR R01 DE024607 Role: Co-I (PI: Shi) 03/2015 - 02/2020 Title: Study of the PorX-PorY Two-component System in Porphyromonas Gingivalis.
BDI-Wei Kong Faculty Startup (PG06496) Role: PI 06/2015 - 11/2019 Title: Engineered Salmonella strains as cancer therapeutics.
NIH/NIAID R01 AI093348 Role: Co-I (PI: Curtiss) 05/2011 - 04/2017 Title: Recombinant Attenuated Bacterial Vaccines Against Biodefense Agents.
Animal Health SRA 13064326 Role: Contract-PI 03/2013 - 05/2015 Title: Attenuated Salmonella vaccines against poultry disease.
NIH/NCI R21 CA152456 Role: PI 06/2010 - 05/2013 Title: Engineered self-destructing Salmonella as a colorectal cancer cure.
USDA 03-35204 Role: Co-I (PI: Curtiss) 08/2003 - 07/2009 Title: Attenuated Salmonella antigen and DNA vaccine delivery vaccines against Eimeria.
Courses
2025 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2024 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2024 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2023 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2023 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2022 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
2022 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2021 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2021 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2020 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2020 Spring
Course Number | Course Title |
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BIO 493 | Honors Thesis |
MIC 495 | Undergraduate Research |
MBB 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
2019 Fall
Course Number | Course Title |
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BIO 492 | Honors Directed Study |
MIC 495 | Undergraduate Research |
BIO 495 | Undergraduate Research |
Salmonella-based vaccine, and cancer immunotherapy. Tulane University School of Medicine. New Orleans, LA, 2022
Tumor navigating microbe-based cancer therapy. International Congress of Cancer & Clinical Oncology, Singapore, 2019
TRAIL-armed self-destructing Salmonella for cancer therapy. International Oncolytic Virus Conference, Oxford, UK, 2018
Microbes-based cancer therapeutics. The meeting of the Cancer Prevention, Detection, Management and Treatment and Viruses, Immunity, Microbiomes and Infectious Disease Divisions, Scottsdale, AZ, 2018
Conference of microbes-based cancer therapeutics. NIH/NCI, 2017
New technology for vaccine delivery. 7th Annual World Vaccine Congress, Nanjing, China, 2015
Development of Salmonella-based vaccine against parasitic diseases. The American Association of Avian Pathologists (AAAP) Annual Meeting, Boston, MA, 2015
Teaching self-destructing Salmonella new tricks to fight cancer. 4th International Conference on Vaccines & Vaccination, Valencia, Spain, 2014
Development of a universal bacterial delivery system for preventive and therapeutic agent delivery. 4th Annual World Congress of Microbes, Dalian, China, 2014
Immunotherapeutics and Vaccine Summit. Boston, MA, 2013
World Vaccine Congress & Expo Washington. Engineering a bacterial antigen and DNA vaccine delivery system. Washington DC, 2013
- Selected as a member of the National Academy of Inventor, 2019
- Faculty Honorees of Skysong Innovations Recognition for U.S. issued patent, 2019
- Faculty Honorees of Skysong Innovations Recognition for U.S. issued patent, 2018
- Faculty Honorees of Skysong Innovations Recognition for U.S. issued patent, 2017
- Faculty Honorees of Skysong Innovations Recognition for U.S. issued patent, 2016
- Faculty Honorees of Skysong Innovations Recognition for a license to Curtiss Healthcare. Inc, 2016
- Faculty Honorees of AzTE Faculty Recognition for an exclusive license to Anivax Inc. 2015
- Prairie Excellence Award, Inner Mongolia of China, 2014
- Faculty Honorees of AzTE Faculty Recognition Event for U.S. issued patent, 2014
- Faculty of 1000 prime, Microbiology, 2013
- Faculty of 1000, Microbiology, 2012
- Faculty of 1000, Biology, 2008
- Academic Editor of PLOS ONE Editorial Board
- Editor, the Editorial Board for EC Bacteriology and Virology Research
- Editor of the Editorial Board for Vaccine Research and Development (VRD)
- American Society for Microbiology (ASM)
- American Association of Avian Pathologists (AAAP)
- American Veterinary Medical Association (AVMA)
Study Sections:
- Reviewer, NIH Translational Immuno-Oncology (TIO) ZRG1 TIO-D (01) Q study section, meeting dates Feb 21-22, Jun 20-21, and Oct. 19-20, 2023
- Reviewer, peer review panel of ZAI1 AWA-M (M1) 1, NIH/NIAID, 2022
- Reviewer, peer review panel of MIDRP and USAMRDC, 2022
- Reviewer, Translational Immuno-Oncology ZRG TIO-D (01) study section, NIH/NCI, 2022
- Reviewer, Immuno-Oncology Research OTC-D08 study section, NIH/NCI, 2022
- Chair, peer review panel for CDMRP/PRMRP, DOD, 2020
- Reviewer, peer review panel for PRMRP/CDMRP, DOD, 2020
- Reviewer, peer review panel of the MIDRP of USAMD, 2020
- Reviewer, peer review panel for PRMRP/CDMRP, DOD, 2019
- Reviewer, peer review panel of the MIDRP of USAMD, 2019
- Chair, peer review panel of the CDMRP/PRMRP, DOD, 2019
- Reviewer, peer review panel of the MIDRP of USAMD, 2018
- Reviewer, peer review panel of the MIDRP of USAMD, 2017
- Reviewer, the Gene and Drug Delivery Systems study section, NIH, 2017
- Reviewer, peer review panel for CDMRP-PRMRP, DOD, 2017
- Chair, peer review panel of the CDMRP/PRMRP, DOD, 2016
- Reviewer, the Partnerships for the Development of Host-Targeted Therapeutics to Limit Antibacterial Resistance (R01) peer review panel for NIH/NIAID, 2016
- Reviewer, peer review panel of the MIDRP of USAMD, 2016
- Reviewer, peer review panel of Small Grants Program for Cancer Research (Ominbus R03) and (R21), NIH/NCI, 2016
- Reviewer, peer review panel for CDMRP-PRMRP, DOD, 2016
- Reviewer, peer review panel of the US Army Medical Research and Material Command (MRMC), 2016
- Chair, peer review panel for CDMRP-PRMRP, DOD, 2015
- Reviewer, the peer review panel of the Military Infections Diseases Research Program of U.S. Army Medical Department (USAMD), 2015
- Reviewer, peer review panel for CDMRP-PRMRP, DOD, 2015
- Reviewer, the peer review panel, PRMRP for CDMRP, 2014
- Reviewer, the peer review panel, Indo-US Collaborative Program, NIH, 2013
- Reviewer, the Early Career Reviewer (ECR) program, NIH, 2013
Institutional Service:
- Fulton Grand Challenges Scholars Program Faculty and Mentor, Ira A. Fulton Schools of engineering, ASU
- Reviewer of the Fulton Grand Challenges Scholars Program, ASU
- Reviewer and Mentor of the Science and Engineering, Experience program (SCENE), ASU
- Mentor of the Mexico-United States Commission for Educational and Cultural Exchange (COMEXUS) program at ASU
- Mentor of the Post-baccalaureate Research Education Programs (PREP), ASU
- Mentor of the School of Life Sciences Undergraduate Research (SOLUR), ASU
- Mentor of the Summer Internship Program (SIP), ASU
- Honors Faculty, Barrett, the Honors College at Arizona State University
- Director of the honors thesis committee, Barrett, the Honors College, ASU
Department service:
- Reviewer of Women and Philanthropy - Internal Competition in the Biodesign Institute, ASU
- Reviewer for student travel funds of the Biodesign institute, ASU
Committee service:
- Co-Chair, Technologies and Mucosal Immunity and Vaccine Design Section, 1st Annual World Vaccine Congress, China
- Co-Chair, DNA Based Vaccines Section, 1st Annual World Vaccine Congress, China